Lung cancer stem cells: The root of resistance.

MacDonagh, Lauren; Gray, Steven G; Breen, Eamon; Cuffe, Sinead; Finn, Stephen P; O'Byrne, Kenneth J; Barr, Martin P

MacDonagh, Lauren; Gray, Steven G; Breen, Eamon; Cuffe, Sinead; Finn, Stephen P; O'Byrne, Kenneth J; Barr, Martin P.

Afiliação

MacDonagh L; Thoracic Oncology Research Group, School of Clinical Medicine, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St. James's Hospital and Trinity College Dublin, Ireland.
Gray SG; Thoracic Oncology Research Group, School of Clinical Medicine, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St. James's Hospital and Trinity College Dublin, Ireland.
Breen E; Flow Cytometry Core Facility, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St. James's Hospital and Trinity College Dublin, Ireland.
Cuffe S; Thoracic Oncology Research Group, School of Clinical Medicine, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St. James's Hospital and Trinity College Dublin, Ireland.
Finn SP; Thoracic Oncology Research Group, School of Clinical Medicine, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St. James's Hospital and Trinity College Dublin, Ireland; Department of Histopathology, St. James's Hospital and Trinity College Dublin, Ireland.
O'Byrne KJ; Cancer & Ageing Research Program, Queensland University of Technology, Brisbane, Australia.
Barr MP; Thoracic Oncology Research Group, School of Clinical Medicine, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St. James's Hospital and Trinity College Dublin, Ireland. Electronic address: mbarr@stjames.ie.

Cancer Lett ; 372(2): 147-56, 2016 Mar 28.

Article em En | MEDLINE | ID: mdl-26797015

Assuntos

Antineoplásicos/uso terapêutico; Resistencia a Medicamentos Antineoplásicos; Neoplasias Pulmonares/tratamento farmacológico; Células-Tronco Neoplásicas/efeitos dos fármacos; Células da Side Population/efeitos dos fármacos; Animais; Biomarcadores Tumorais/genética; Biomarcadores Tumorais/metabolismo; Diferenciação Celular/efeitos dos fármacos; Proliferação de Células/efeitos dos fármacos; Resistencia a Medicamentos Antineoplásicos/genética; Humanos; Neoplasias Pulmonares/genética; Neoplasias Pulmonares/metabolismo; Neoplasias Pulmonares/patologia; Terapia de Alvo Molecular; Células-Tronco Neoplásicas/metabolismo; Células-Tronco Neoplásicas/patologia; Fenótipo; Células da Side Population/metabolismo; Células da Side Population/patologia; Transdução de Sinais/efeitos dos fármacos

Palavras-chave

Cancer stem cells; Chemotherapy; Lung cancer; Markers; Resistance

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Neoplásicas / Resistencia a Medicamentos Antineoplásicos / Células da Side Population / Neoplasias Pulmonares / Antineoplásicos Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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