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Causal Assessment of Serum Urate Levels in Cardiometabolic Diseases Through a Mendelian Randomization Study.
Keenan, Tanya; Zhao, Wei; Rasheed, Asif; Ho, Weang K; Malik, Rainer; Felix, Janine F; Young, Robin; Shah, Nabi; Samuel, Maria; Sheikh, Nasir; Mucksavage, Megan L; Shah, Omar; Li, Jin; Morley, Michael; Laser, Annika; Mallick, Nadeem Hayat; Zaman, Khan Shah; Ishaq, Mohammad; Rasheed, Syed Zahed; Memon, Fazal-Ur-Rehman; Ahmed, Faisal; Hanif, Bashir; Lakhani, Muhammad Shakir; Fahim, Muhammad; Ishaq, Madiha; Shardha, Naresh Kumar; Ahmed, Naveeduddin; Mahmood, Khalid; Iqbal, Waseem; Akhtar, Saba; Raheel, Rabia; O'Donnell, Christopher J; Hengstenberg, Christian; März, Winifred; Kathiresan, Sekar; Samani, Nilesh; Goel, Anuj; Hopewell, Jemma C; Chambers, John; Cheng, Yu-Ching; Sharma, Pankaj; Yang, Qiong; Rosand, Jonathan; Boncoraglio, Giorgio B; Kazmi, Shahana Urooj; Hakonarson, Hakon; Köttgen, Anna; Kalogeropoulos, Andreas; Frossard, Philippe; Kamal, Ayeesha.
Afiliação
  • Keenan T; Translational Medicine and Human Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts.
  • Zhao W; Translational Medicine and Human Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Rasheed A; Center for Non-Communicable Diseases, Karachi, Pakistan.
  • Ho WK; Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.
  • Malik R; Ludwig-Maximilians-University Munich, Medical Center, Institute for Stroke and Dementia Research (ISD), Munich, Germany.
  • Felix JF; Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, the Netherlands and The Netherlands Genomics Initiative, Netherlands Consortium for Healthy Aging (NGI-NCHA), Leiden, the Netherlands.
  • Young R; Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.
  • Shah N; Center for Non-Communicable Diseases, Karachi, Pakistan.
  • Samuel M; Center for Non-Communicable Diseases, Karachi, Pakistan.
  • Sheikh N; Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.
  • Mucksavage ML; Translational Medicine and Human Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Shah O; Translational Medicine and Human Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Li J; Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
  • Morley M; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Laser A; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, Neuherberg, Germany; Institute of Epidemiology II, Helmholtz Zentrum München, Neuherberg, Germany.
  • Mallick NH; Punjab Institute of Cardiology, Lahore, Pakistan.
  • Zaman KS; National Institute of Cardiovascular Diseases, Karachi, Pakistan.
  • Ishaq M; Karachi Institute of Heart Diseases, Karachi, Pakistan.
  • Rasheed SZ; Karachi Institute of Heart Diseases, Karachi, Pakistan.
  • Memon FU; Red Crescent Institute of Cardiology, Hyderabad, Pakistan.
  • Ahmed F; Department of Cardiology, Liaquat National Hospital, Karachi, Pakistan.
  • Hanif B; Department of Cardiology, Tabba Heart Institute, Karachi, Pakistan.
  • Lakhani MS; Department of Cardiology, Tabba Heart Institute, Karachi, Pakistan.
  • Fahim M; Center for Non-Communicable Diseases, Karachi, Pakistan.
  • Ishaq M; Center for Non-Communicable Diseases, Karachi, Pakistan.
  • Shardha NK; Center for Non-Communicable Diseases, Karachi, Pakistan.
  • Ahmed N; Department of Neurology, Liaquat National Hospital, Karachi, Pakistan.
  • Mahmood K; Department of Medicine, Dow University of Health Sciences, Civil Hospital, Karachi, Pakistan.
  • Iqbal W; Department of Medicine, Lahore General Hospital, Lahore, Pakistan.
  • Akhtar S; Center for Non-Communicable Diseases, Karachi, Pakistan.
  • Raheel R; Center for Non-Communicable Diseases, Karachi, Pakistan.
  • O'Donnell CJ; National Heart, Lung, and Blood Institute Framingham Heart Study, Framingham, Massachusetts; Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts; Department of Medicine, Harvard Medical School, Boston, Massachusetts.
  • Hengstenberg C; Internal Medicine II - Cardiology, University Hospital of Regensburg, Regensburg, Germany.
  • März W; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria; Medical Clinic V, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany; Synlab Academy, Synlab Laboratory Services GmbH, Mannheim, Germany.
  • Kathiresan S; Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts; Department of Medicine, Harvard Medical School, Boston, Massachusetts; Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts; Program in Medical and Population Genetics, Broad In
  • Samani N; Department of Cardiovascular Sciences, University of Leicester, Clinical Sciences Wing, Glenfield General Hospital, Leicester, United Kingdom.
  • Goel A; Wellcome Trust Center for Human Genetics, University of Oxford, Oxford, United Kingdom.
  • Hopewell JC; Division of Cardiovascular Science, Oxford University, Oxford, United Kingdom.
  • Chambers J; School of Public Health, Imperial College, London, United Kingdom.
  • Cheng YC; Department of Medicine, University of Maryland School of Medicine, Baltimore VA Medical Center, Baltimore, Maryland.
  • Sharma P; Imperial College London & Hammersmith Hospitals, London, United Kingdom.
  • Yang Q; School of Public Health, Boston University, Boston, Massachusetts.
  • Rosand J; Division of Neurocritical Care, Massachusetts General Hospital, Boston, Massachusetts.
  • Boncoraglio GB; Department of Cerebrovascular Diseases, Fondazione IRCCS Istituto Neurologico, Milan, Italy.
  • Kazmi SU; Department of Microbiology, University of Karachi, Karachi, Pakistan.
  • Hakonarson H; Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
  • Köttgen A; Renal Division, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
  • Kalogeropoulos A; Division of Cardiology, School of Medicine, Emory University, Atlanta, Georgia.
  • Frossard P; Center for Non-Communicable Diseases, Karachi, Pakistan.
  • Kamal A; Division of Neurology, Department of Medicine, Aga Khan University, Karachi, Pakistan.
J Am Coll Cardiol ; 67(4): 407-416, 2016 Feb 02.
Article em En | MEDLINE | ID: mdl-26821629
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácido Úrico / Medição de Risco / Doença das Coronárias / Acidente Vascular Cerebral / Polimorfismo de Nucleotídeo Único / Diabetes Mellitus Tipo 2 / Análise da Randomização Mendeliana Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácido Úrico / Medição de Risco / Doença das Coronárias / Acidente Vascular Cerebral / Polimorfismo de Nucleotídeo Único / Diabetes Mellitus Tipo 2 / Análise da Randomização Mendeliana Idioma: En Ano de publicação: 2016 Tipo de documento: Article