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Unique features of a global human ectoparasite identified through sequencing of the bed bug genome.
Benoit, Joshua B; Adelman, Zach N; Reinhardt, Klaus; Dolan, Amanda; Poelchau, Monica; Jennings, Emily C; Szuter, Elise M; Hagan, Richard W; Gujar, Hemant; Shukla, Jayendra Nath; Zhu, Fang; Mohan, M; Nelson, David R; Rosendale, Andrew J; Derst, Christian; Resnik, Valentina; Wernig, Sebastian; Menegazzi, Pamela; Wegener, Christian; Peschel, Nicolai; Hendershot, Jacob M; Blenau, Wolfgang; Predel, Reinhard; Johnston, Paul R; Ioannidis, Panagiotis; Waterhouse, Robert M; Nauen, Ralf; Schorn, Corinna; Ott, Mark-Christoph; Maiwald, Frank; Johnston, J Spencer; Gondhalekar, Ameya D; Scharf, Michael E; Peterson, Brittany F; Raje, Kapil R; Hottel, Benjamin A; Armisén, David; Crumière, Antonin Jean Johan; Refki, Peter Nagui; Santos, Maria Emilia; Sghaier, Essia; Viala, Sèverine; Khila, Abderrahman; Ahn, Seung-Joon; Childers, Christopher; Lee, Chien-Yueh; Lin, Han; Hughes, Daniel S T; Duncan, Elizabeth J; Murali, Shwetha C.
Afiliação
  • Benoit JB; Department of Biological Sciences, University of Cincinnati, Cincinnati, Ohio 45221, USA.
  • Adelman ZN; Fralin Life Science Institute and Department of Entomology, Virginia Tech, Blacksburg, Virginia 24061, USA.
  • Reinhardt K; Department of Biology, Applied Zoology, Technische Universitaet Dresden, Dresden 01062, Germany.
  • Dolan A; Department of Biology, University of Rochester, Rochester, New York 14627, USA.
  • Poelchau M; National Agricultural Library, Beltsville, Maryland 20705, USA.
  • Jennings EC; Department of Biological Sciences, University of Cincinnati, Cincinnati, Ohio 45221, USA.
  • Szuter EM; Department of Biological Sciences, University of Cincinnati, Cincinnati, Ohio 45221, USA.
  • Hagan RW; Department of Biological Sciences, University of Cincinnati, Cincinnati, Ohio 45221, USA.
  • Gujar H; Department of Entomology, University of Kentucky, Lexington, Kentucky 40546, USA.
  • Shukla JN; Department of Entomology, University of Kentucky, Lexington, Kentucky 40546, USA.
  • Zhu F; Department of Entomology, University of Kentucky, Lexington, Kentucky 40546, USA.
  • Mohan M; Department of Entomology, Washington State University, Pullman, Washington 99164, USA.
  • Nelson DR; ICAR-National Bureau of Agricultural Insect Resources, Indian Council of Agricultural Research, Bengaluru 560024, India.
  • Rosendale AJ; Department of Microbiology, Immunology, and Biochemistry, University of Tennessee Health Sciences Center, Memphis, Tennessee 38163, USA.
  • Derst C; Department of Biological Sciences, University of Cincinnati, Cincinnati, Ohio 45221, USA.
  • Resnik V; Cologne Biocenter and Zoological Institute, University of Cologne, Cologne 50674, Germany.
  • Wernig S; Institut für Bienenkunde (Polytechnische Gesellschaft), Goethe University Frankfurt, Oberursel 61440, Germany.
  • Menegazzi P; Institut für Bienenkunde (Polytechnische Gesellschaft), Goethe University Frankfurt, Oberursel 61440, Germany.
  • Wegener C; Department of Neurobiology and Genetics, Theodor-Boveri-Institute, Biocenter, University of Würzburg, Würzburg 97074, Germany.
  • Peschel N; Department of Neurobiology and Genetics, Theodor-Boveri-Institute, Biocenter, University of Würzburg, Würzburg 97074, Germany.
  • Hendershot JM; Department of Neurobiology and Genetics, Theodor-Boveri-Institute, Biocenter, University of Würzburg, Würzburg 97074, Germany.
  • Blenau W; Department of Biological Sciences, University of Cincinnati, Cincinnati, Ohio 45221, USA.
  • Predel R; Cologne Biocenter and Zoological Institute, University of Cologne, Cologne 50674, Germany.
  • Johnston PR; Cologne Biocenter and Zoological Institute, University of Cologne, Cologne 50674, Germany.
  • Ioannidis P; Department of Evolutionary Biology, Institute of Biology, Freie Universitaet, Berlin 14195, Germany.
  • Waterhouse RM; Department of Genetic Medicine and Development and Swiss Institute of Bioinformatics, University of Geneva, Geneva 1211, Switzerland.
  • Nauen R; Department of Genetic Medicine and Development and Swiss Institute of Bioinformatics, University of Geneva, Geneva 1211, Switzerland.
  • Schorn C; Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology and The Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02139, USA.
  • Ott MC; Pest Control Biology and Research Technologies, Bayer CropScience AG, Monheim 40789, Germany.
  • Maiwald F; Pest Control Biology and Research Technologies, Bayer CropScience AG, Monheim 40789, Germany.
  • Johnston JS; Pest Control Biology and Research Technologies, Bayer CropScience AG, Monheim 40789, Germany.
  • Gondhalekar AD; Pest Control Biology and Research Technologies, Bayer CropScience AG, Monheim 40789, Germany.
  • Scharf ME; Department of Entomology, Texas A&M University, College Station, Texas 77843, USA.
  • Peterson BF; Department of Entomology, Purdue University, West Lafayette, Indiana 47907, USA.
  • Raje KR; Department of Entomology, Purdue University, West Lafayette, Indiana 47907, USA.
  • Hottel BA; Department of Entomology, Purdue University, West Lafayette, Indiana 47907, USA.
  • Armisén D; Department of Entomology, Purdue University, West Lafayette, Indiana 47907, USA.
  • Crumière AJJ; Department of Entomology and Nematology, University of Florida, Gainesville, Florida 32611, USA.
  • Refki PN; Institue de Génomique Fonctionnelle de Lyon (IGFL), Ecole Normale Supérieure de Lyon, UMR5242-CNRS, Lyon 69007, France.
  • Santos ME; Institue de Génomique Fonctionnelle de Lyon (IGFL), Ecole Normale Supérieure de Lyon, UMR5242-CNRS, Lyon 69007, France.
  • Sghaier E; Institue de Génomique Fonctionnelle de Lyon (IGFL), Ecole Normale Supérieure de Lyon, UMR5242-CNRS, Lyon 69007, France.
  • Viala S; Institue de Génomique Fonctionnelle de Lyon (IGFL), Ecole Normale Supérieure de Lyon, UMR5242-CNRS, Lyon 69007, France.
  • Khila A; Institue de Génomique Fonctionnelle de Lyon (IGFL), Ecole Normale Supérieure de Lyon, UMR5242-CNRS, Lyon 69007, France.
  • Ahn SJ; Institue de Génomique Fonctionnelle de Lyon (IGFL), Ecole Normale Supérieure de Lyon, UMR5242-CNRS, Lyon 69007, France.
  • Childers C; Institue de Génomique Fonctionnelle de Lyon (IGFL), Ecole Normale Supérieure de Lyon, UMR5242-CNRS, Lyon 69007, France.
  • Lee CY; Department of Entomology, Max Planck Institute for Chemical Ecology, Jena 07745, Germany.
  • Lin H; National Agricultural Library, Beltsville, Maryland 20705, USA.
  • Hughes DST; National Agricultural Library, Beltsville, Maryland 20705, USA.
  • Duncan EJ; Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei 10617, Taiwan.
  • Murali SC; National Agricultural Library, Beltsville, Maryland 20705, USA.
Nat Commun ; 7: 10165, 2016 Feb 02.
Article em En | MEDLINE | ID: mdl-26836814
ABSTRACT
The bed bug, Cimex lectularius, has re-established itself as a ubiquitous human ectoparasite throughout much of the world during the past two decades. This global resurgence is likely linked to increased international travel and commerce in addition to widespread insecticide resistance. Analyses of the C. lectularius sequenced genome (650 Mb) and 14,220 predicted protein-coding genes provide a comprehensive representation of genes that are linked to traumatic insemination, a reduced chemosensory repertoire of genes related to obligate hematophagy, host-symbiont interactions, and several mechanisms of insecticide resistance. In addition, we document the presence of multiple putative lateral gene transfer events. Genome sequencing and annotation establish a solid foundation for future research on mechanisms of insecticide resistance, human-bed bug and symbiont-bed bug associations, and unique features of bed bug biology that contribute to the unprecedented success of C. lectularius as a human ectoparasite.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Percevejos-de-Cama / Resistência a Inseticidas / Transferência Genética Horizontal / Ectoparasitoses / Comportamento Alimentar / Interações Hospedeiro-Parasita / Inseticidas Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Percevejos-de-Cama / Resistência a Inseticidas / Transferência Genética Horizontal / Ectoparasitoses / Comportamento Alimentar / Interações Hospedeiro-Parasita / Inseticidas Idioma: En Ano de publicação: 2016 Tipo de documento: Article