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A G Protein-biased Designer G Protein-coupled Receptor Useful for Studying the Physiological Relevance of Gq/11-dependent Signaling Pathways.
Hu, Jianxin; Stern, Matthew; Gimenez, Luis E; Wanka, Lizzy; Zhu, Lu; Rossi, Mario; Meister, Jaroslawna; Inoue, Asuka; Beck-Sickinger, Annette G; Gurevich, Vsevolod V; Wess, Jürgen.
Afiliação
  • Hu J; From the Molecular Signaling Section, Laboratory of Bioorganic Chemistry, NIDDK, National Institutes of Health, Bethesda, Maryland 20892.
  • Stern M; From the Molecular Signaling Section, Laboratory of Bioorganic Chemistry, NIDDK, National Institutes of Health, Bethesda, Maryland 20892.
  • Gimenez LE; the Vanderbilt University Medical Center, Nashville, Tennessee 37232.
  • Wanka L; the Institute of Biochemistry, University of Leipzig, Leipzig 04103, Germany.
  • Zhu L; From the Molecular Signaling Section, Laboratory of Bioorganic Chemistry, NIDDK, National Institutes of Health, Bethesda, Maryland 20892.
  • Rossi M; From the Molecular Signaling Section, Laboratory of Bioorganic Chemistry, NIDDK, National Institutes of Health, Bethesda, Maryland 20892.
  • Meister J; From the Molecular Signaling Section, Laboratory of Bioorganic Chemistry, NIDDK, National Institutes of Health, Bethesda, Maryland 20892.
  • Inoue A; the Graduate School of Pharmaceutical Science, Tohoku University, Sendai, Miyagi 980-8578, Japan, and the Japan Science and Technology Agency, Precursory Research for Embryonic Science and Technology (PRESTO), Kawaguchi, Saitama 332-0012, Japan.
  • Beck-Sickinger AG; the Institute of Biochemistry, University of Leipzig, Leipzig 04103, Germany.
  • Gurevich VV; the Vanderbilt University Medical Center, Nashville, Tennessee 37232.
  • Wess J; From the Molecular Signaling Section, Laboratory of Bioorganic Chemistry, NIDDK, National Institutes of Health, Bethesda, Maryland 20892, jwess@helix.nih.gov.
J Biol Chem ; 291(15): 7809-20, 2016 Apr 08.
Article em En | MEDLINE | ID: mdl-26851281

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Hepatócitos / Mapeamento de Interação de Proteínas / Subunidades alfa Gq-G11 de Proteínas de Ligação ao GTP / Receptores Acoplados a Proteínas G Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Hepatócitos / Mapeamento de Interação de Proteínas / Subunidades alfa Gq-G11 de Proteínas de Ligação ao GTP / Receptores Acoplados a Proteínas G Idioma: En Ano de publicação: 2016 Tipo de documento: Article