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Structural Decoding of the Netrin-1/UNC5 Interaction and its Therapeutical Implications in Cancers.
Grandin, Mélodie; Meier, Markus; Delcros, Jean Guy; Nikodemus, Denise; Reuten, Raphael; Patel, Trushar R; Goldschneider, David; Orriss, George; Krahn, Natalie; Boussouar, Amina; Abes, Riad; Dean, Yann; Neves, David; Bernet, Agnes; Depil, Stephane; Schneiders, Fiona; Poole, Kate; Dante, Robert; Koch, Manuel; Mehlen, Patrick; Stetefeld, Jörg.
Afiliação
  • Grandin M; Apoptosis, Cancer and Development Laboratory, Equipe labellisée 'La Ligue', LabEx DEVweCAN, Centre de Recherche en Cancérologie de Lyon, INSERM U1052-CNRS UMR5286, Université de Lyon, Centre Léon Bérard, 69008 Lyon, France.
  • Meier M; Department of Chemistry, University of Manitoba, 144 Dysart Road, Winnipeg, MB RT3 2N2, Canada.
  • Delcros JG; Apoptosis, Cancer and Development Laboratory, Equipe labellisée 'La Ligue', LabEx DEVweCAN, Centre de Recherche en Cancérologie de Lyon, INSERM U1052-CNRS UMR5286, Université de Lyon, Centre Léon Bérard, 69008 Lyon, France.
  • Nikodemus D; Center for Biochemistry, Institute for Dental Research and Oral Musculoskeletal Research, University of Cologne, 50931 Cologne, Germany; Centre for Ecology, Evolution and Environmental Changes, Faculdade de Ciências, Universidade de Lisboa, Lisbon 1749-016, Portugal.
  • Reuten R; Center for Biochemistry, Institute for Dental Research and Oral Musculoskeletal Research, University of Cologne, 50931 Cologne, Germany.
  • Patel TR; Department of Chemistry, University of Manitoba, 144 Dysart Road, Winnipeg, MB RT3 2N2, Canada; Department of Microbiology, University of Manitoba, 144 Dysart Road, Winnipeg, MB RT3 2N2, Canada.
  • Goldschneider D; Apoptosis, Cancer and Development Laboratory, Equipe labellisée 'La Ligue', LabEx DEVweCAN, Centre de Recherche en Cancérologie de Lyon, INSERM U1052-CNRS UMR5286, Université de Lyon, Centre Léon Bérard, 69008 Lyon, France; Netris Pharma, Centre Léon Bérard, 69008 Lyon, France.
  • Orriss G; Department of Chemistry, University of Manitoba, 144 Dysart Road, Winnipeg, MB RT3 2N2, Canada.
  • Krahn N; Department of Chemistry, University of Manitoba, 144 Dysart Road, Winnipeg, MB RT3 2N2, Canada.
  • Boussouar A; Apoptosis, Cancer and Development Laboratory, Equipe labellisée 'La Ligue', LabEx DEVweCAN, Centre de Recherche en Cancérologie de Lyon, INSERM U1052-CNRS UMR5286, Université de Lyon, Centre Léon Bérard, 69008 Lyon, France.
  • Abes R; Netris Pharma, Centre Léon Bérard, 69008 Lyon, France.
  • Dean Y; Netris Pharma, Centre Léon Bérard, 69008 Lyon, France.
  • Neves D; Netris Pharma, Centre Léon Bérard, 69008 Lyon, France.
  • Bernet A; Apoptosis, Cancer and Development Laboratory, Equipe labellisée 'La Ligue', LabEx DEVweCAN, Centre de Recherche en Cancérologie de Lyon, INSERM U1052-CNRS UMR5286, Université de Lyon, Centre Léon Bérard, 69008 Lyon, France; Netris Pharma, Centre Léon Bérard, 69008 Lyon, France.
  • Depil S; Netris Pharma, Centre Léon Bérard, 69008 Lyon, France.
  • Schneiders F; Center for Biochemistry, Institute for Dental Research and Oral Musculoskeletal Research, University of Cologne, 50931 Cologne, Germany.
  • Poole K; Department of Neuroscience, Max-Delbrück Center for Molecular Medicine, Robert-Rössle Straße 10, Berlin 13092, Germany.
  • Dante R; Apoptosis, Cancer and Development Laboratory, Equipe labellisée 'La Ligue', LabEx DEVweCAN, Centre de Recherche en Cancérologie de Lyon, INSERM U1052-CNRS UMR5286, Université de Lyon, Centre Léon Bérard, 69008 Lyon, France.
  • Koch M; Center for Biochemistry, Institute for Dental Research and Oral Musculoskeletal Research, University of Cologne, 50931 Cologne, Germany; Centre for Ecology, Evolution and Environmental Changes, Faculdade de Ciências, Universidade de Lisboa, Lisbon 1749-016, Portugal.
  • Mehlen P; Apoptosis, Cancer and Development Laboratory, Equipe labellisée 'La Ligue', LabEx DEVweCAN, Centre de Recherche en Cancérologie de Lyon, INSERM U1052-CNRS UMR5286, Université de Lyon, Centre Léon Bérard, 69008 Lyon, France. Electronic address: patrick.mehlen@lyon.unicancer.fr.
  • Stetefeld J; Department of Chemistry, University of Manitoba, 144 Dysart Road, Winnipeg, MB RT3 2N2, Canada. Electronic address: jorg.stetefeld@ad.manitoba.ca.
Cancer Cell ; 29(2): 173-85, 2016 Feb 08.
Article em En | MEDLINE | ID: mdl-26859457
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores de Superfície Celular / Proteínas Supressoras de Tumor / Neoplasias / Fatores de Crescimento Neural Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores de Superfície Celular / Proteínas Supressoras de Tumor / Neoplasias / Fatores de Crescimento Neural Idioma: En Ano de publicação: 2016 Tipo de documento: Article