Colon Cancer Tumorigenesis Initiated by the H1047R Mutant PI3K.

Yueh, Alexander E; Payne, Susan N; Leystra, Alyssa A; Van De Hey, Dana R; Foley, Tyler M; Pasch, Cheri A; Clipson, Linda; Matkowskyj, Kristina A; Deming, Dustin A

Yueh, Alexander E; Payne, Susan N; Leystra, Alyssa A; Van De Hey, Dana R; Foley, Tyler M; Pasch, Cheri A; Clipson, Linda; Matkowskyj, Kristina A; Deming, Dustin A.

Afiliação

Yueh AE; Division of Hematology and Oncology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States of America.
Payne SN; University of Wisconsin Carbone Cancer Center, Madison, WI, United States of America.
Leystra AA; Department of Oncology, University of Wisconsin Madison, Madison, WI, United States of America.
Van De Hey DR; Division of Hematology and Oncology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States of America.
Foley TM; Division of Hematology and Oncology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States of America.
Pasch CA; University of Wisconsin Carbone Cancer Center, Madison, WI, United States of America.
Clipson L; Department of Oncology, University of Wisconsin Madison, Madison, WI, United States of America.
Matkowskyj KA; University of Wisconsin Carbone Cancer Center, Madison, WI, United States of America.
Deming DA; Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States of America.

PLoS One ; 11(2): e0148730, 2016.

Article em En | MEDLINE | ID: mdl-26863299

Assuntos

Adenocarcinoma/genética; Neoplasias do Colo/genética; Fosfatidilinositol 3-Quinases/genética; Adenocarcinoma/tratamento farmacológico; Adenocarcinoma/enzimologia; Adenocarcinoma/patologia; Animais; Antineoplásicos/farmacologia; Carcinogênese/genética; Classe I de Fosfatidilinositol 3-Quinases; Neoplasias do Colo/tratamento farmacológico; Neoplasias do Colo/enzimologia; Neoplasias do Colo/patologia; Ensaios de Seleção de Medicamentos Antitumorais; Feminino; Estudos de Associação Genética; Predisposição Genética para Doença; Imidazóis/farmacologia; Masculino; Camundongos Endogâmicos C57BL; Camundongos Transgênicos; Mutação de Sentido Incorreto; Inibidores de Fosfoinositídeo-3 Quinase; Quinolinas/farmacologia; Serina-Treonina Quinases TOR/antagonistas & inibidores; Carga Tumoral/efeitos dos fármacos

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Adenocarcinoma / Neoplasias do Colo / Fosfatidilinositol 3-Quinases Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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