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Flexible double-headed cytosine-linked 2'-deoxycytidine nucleotides. Synthesis, polymerase incorporation to DNA and interaction with DNA methyltransferases.
Kielkowski, Pavel; Cahová, Hana; Pohl, Radek; Hocek, Michal.
Afiliação
  • Kielkowski P; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Gilead Sciences & IOCB Research Center, Flemingovo nám. 2, CZ-16610 Prague 6, Czech Republic.
  • Cahová H; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Gilead Sciences & IOCB Research Center, Flemingovo nám. 2, CZ-16610 Prague 6, Czech Republic.
  • Pohl R; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Gilead Sciences & IOCB Research Center, Flemingovo nám. 2, CZ-16610 Prague 6, Czech Republic.
  • Hocek M; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Gilead Sciences & IOCB Research Center, Flemingovo nám. 2, CZ-16610 Prague 6, Czech Republic; Department of Organic Chemistry, Faculty of Science, Charles University in Prague, Hlavova 8, CZ-12843 Prague
Bioorg Med Chem ; 24(6): 1268-76, 2016 Mar 15.
Article em En | MEDLINE | ID: mdl-26899597
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA / Citosina / Nucleotídeos de Desoxicitosina / DNA (Citosina-5-)-Metiltransferases / DNA Polimerase Dirigida por DNA Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA / Citosina / Nucleotídeos de Desoxicitosina / DNA (Citosina-5-)-Metiltransferases / DNA Polimerase Dirigida por DNA Idioma: En Ano de publicação: 2016 Tipo de documento: Article