AGTR1 has undergone natural selection in Euro-Asian populations in relation to ambient temperature that predisposes Chinese populations to essential hypertension.

Ji, Lin-Dan; Tang, Nelson L S; Xu, Jin

Ji, Lin-Dan; Tang, Nelson L S; Xu, Jin.

Afiliação

Ji LD; Department of Biochemistry, School of Medicine, Ningbo University, Ningbo, China; State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.
Tang NL; Department of Chemical Pathology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China; Laboratory for Genetics of Disease Susceptibility, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Xu J; State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China; Department of Preventive Medicine, School of Medicine, Ningbo University, Ningbo, China. Electronic address: xujin1@nbu.edu.cn.

Int J Cardiol ; 209: 278-80, 2016 Apr 15.

Article em En | MEDLINE | ID: mdl-26901789

Assuntos

Povo Asiático/genética; Hipertensão/genética; Receptor Tipo 1 de Angiotensina/genética; Seleção Genética/genética; População Branca/genética; Hipertensão Essencial; Humanos; Hipertensão/diagnóstico; Polimorfismo de Nucleotídeo Único/genética; Temperatura

Palavras-chave

AGTR1; Ambient temperature; Genetic susceptibility; Hypertension; Natural selection; Reninangiotensinaldosterone system

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Seleção Genética / Receptor Tipo 1 de Angiotensina / Povo Asiático / População Branca / Hipertensão Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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