A New Specific Device in Transcatheter Prosthetic Paravalvular Leak Closure: A Prospective Two-Center Trial.
Catheter Cardiovasc Interv
; 88(4): 618-624, 2016 Oct.
Article
em En
| MEDLINE
| ID: mdl-26909784
ABSTRACT
BACKGROUND:
This study sought to compare various outcomes among a new specifically designed transcatheter paravalvular leak closure (TPVLC) device and the devices that are being utilized off-label.METHODS:
Between April 2012 and January 2015, in a prospective two-center study, 52 patients who needed surgical reintervention due to a hemodynamically significant prosthetic paravalvular leak were studied. This study population was divided into two groups. Group I was composed of 32 patients who underwent paravalvular leak (PVL) closure with the currently available devices that are being utilized off-label, while group II consisted of 20 patients who were treated with the new specifically designed Occlutech PVL device.RESULTS:
Demographic and clinical variables indicated a higher rate of atrial fibrillation (P = 0.027) and chronic obstructive airway disease (P = 0.009) in group II. The apical approach was the most commonly used intervention route used for group II (P = 0.019). The procedural success rate was 100% (29 of 29 leaks) in group II while the rate was 92% (39 of 42 leaks) in group I. However, more secondary events were observed in group I, but they did not reach statistical significance (8 vs. 1, P = 0.064).CONCLUSIONS:
With its high procedural success rate and encouraging outcome results, the Occlutech device seems to satisfy the expectations of a specifically designed PVL closure device. © 2016 Wiley Periodicals, Inc.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Falha de Prótese
/
Cateterismo Cardíaco
/
Implante de Prótese de Valva Cardíaca
/
Insuficiência Cardíaca
/
Doenças das Valvas Cardíacas
/
Valvas Cardíacas
/
Hemólise
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article