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Dual regulatory switch through interactions of Tcf7l2/Tcf4 with stage-specific partners propels oligodendroglial maturation.
Zhao, Chuntao; Deng, Yaqi; Liu, Lei; Yu, Kun; Zhang, Liguo; Wang, Haibo; He, Xuelian; Wang, Jincheng; Lu, Changqing; Wu, Laiman N; Weng, Qinjie; Mao, Meng; Li, Jianrong; van Es, Johan H; Xin, Mei; Parry, Lee; Goldman, Steven A; Clevers, Hans; Lu, Q Richard.
Afiliação
  • Zhao C; Department of Pediatrics, State Key Laboratory of Biotherapy, West China Second Hospital, Sichuan University, Collaborative Innovation Center for Biotherapy, Chengdu 610041, China.
  • Deng Y; Division of Experimental Hematology and Cancer Biology, Department of Pediatrics, Brain Tumor Center, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.
  • Liu L; Department of Pediatrics, State Key Laboratory of Biotherapy, West China Second Hospital, Sichuan University, Collaborative Innovation Center for Biotherapy, Chengdu 610041, China.
  • Yu K; Division of Experimental Hematology and Cancer Biology, Department of Pediatrics, Brain Tumor Center, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.
  • Zhang L; Department of Pediatrics, State Key Laboratory of Biotherapy, West China Second Hospital, Sichuan University, Collaborative Innovation Center for Biotherapy, Chengdu 610041, China.
  • Wang H; Key Laboratory of Obstetrics, and Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education, West China Second Hospital, Sichuan University, Collaborative Innovation Center for Biotherapy, Chengdu 610041, China.
  • He X; Department of Pediatrics, State Key Laboratory of Biotherapy, West China Second Hospital, Sichuan University, Collaborative Innovation Center for Biotherapy, Chengdu 610041, China.
  • Wang J; Division of Experimental Hematology and Cancer Biology, Department of Pediatrics, Brain Tumor Center, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.
  • Lu C; Division of Experimental Hematology and Cancer Biology, Department of Pediatrics, Brain Tumor Center, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.
  • Wu LN; Division of Experimental Hematology and Cancer Biology, Department of Pediatrics, Brain Tumor Center, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.
  • Weng Q; Division of Experimental Hematology and Cancer Biology, Department of Pediatrics, Brain Tumor Center, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.
  • Mao M; Institute of Pharmacology and Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
  • Li J; Department of Pediatrics, State Key Laboratory of Biotherapy, West China Second Hospital, Sichuan University, Collaborative Innovation Center for Biotherapy, Chengdu 610041, China.
  • van Es JH; Division of Experimental Hematology and Cancer Biology, Department of Pediatrics, Brain Tumor Center, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.
  • Xin M; Institute of Pharmacology and Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
  • Parry L; Key Laboratory of Obstetrics, and Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education, West China Second Hospital, Sichuan University, Collaborative Innovation Center for Biotherapy, Chengdu 610041, China.
  • Goldman SA; Department of Veterinary Integrative Biosciences, Texas A&M University, College Station, Texas 77843, USA.
  • Clevers H; Hubrecht Institute, Uppsalalaan 8, Utrecht 3584CT, The Netherlands.
  • Lu QR; Division of Experimental Hematology and Cancer Biology, Department of Pediatrics, Brain Tumor Center, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.
Nat Commun ; 7: 10883, 2016 Mar 09.
Article em En | MEDLINE | ID: mdl-26955760
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Oligodendroglia / Regulação da Expressão Gênica no Desenvolvimento / Fatores de Transcrição SOXE / Proteína 2 Semelhante ao Fator 7 de Transcrição / Sistema Nervoso Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Oligodendroglia / Regulação da Expressão Gênica no Desenvolvimento / Fatores de Transcrição SOXE / Proteína 2 Semelhante ao Fator 7 de Transcrição / Sistema Nervoso Idioma: En Ano de publicação: 2016 Tipo de documento: Article