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Characterization of chemical-induced sterile inflammation in vitro: application of the model compound ketoconazole in a human hepatic co-culture system.
Wewering, Franziska; Jouy, Florent; Wissenbach, Dirk K; Gebauer, Scarlett; Blüher, Matthias; Gebhardt, Rolf; Pirow, Ralph; von Bergen, Martin; Kalkhof, Stefan; Luch, Andreas; Zellmer, Sebastian.
Afiliação
  • Wewering F; Department of Chemical and Product Safety, German Federal Institute for Risk Assessment (BfR), Max-Dohrn-Strasse 8-10, 10589, Berlin, Germany. franziska.wewering@bfr.bund.de.
  • Jouy F; Department of Proteomics, UFZ, Helmholtz-Centre for Environmental Research, Permoserstrasse 15, 04318, Leipzig, Germany.
  • Wissenbach DK; Department of Metabolomics, UFZ, Helmholtz-Centre for Environmental Research, Permoserstrasse 15, 04318, Leipzig, Germany.
  • Gebauer S; Institute of Forensic Medicine, Jena University Hospital, 07743, Jena, Germany.
  • Blüher M; Department of Metabolomics, UFZ, Helmholtz-Centre for Environmental Research, Permoserstrasse 15, 04318, Leipzig, Germany.
  • Gebhardt R; Clinic for Endocrinology and Nephrology, Faculty of Medicine, University of Leipzig, Liebigstrasse 20, 04103, Leipzig, Germany.
  • Pirow R; Institute of Biochemistry, Faculty of Medicine, University of Leipzig, Johannisallee 30, 04103, Leipzig, Germany.
  • von Bergen M; Department of Chemical and Product Safety, German Federal Institute for Risk Assessment (BfR), Max-Dohrn-Strasse 8-10, 10589, Berlin, Germany.
  • Kalkhof S; Department of Proteomics, UFZ, Helmholtz-Centre for Environmental Research, Permoserstrasse 15, 04318, Leipzig, Germany.
  • Luch A; Department of Metabolomics, UFZ, Helmholtz-Centre for Environmental Research, Permoserstrasse 15, 04318, Leipzig, Germany.
  • Zellmer S; Department of Life Sciences and Chemistry, Centre for Microbial Communities, University of Aalborg, Sohngaardsholmsvej 49, 9000, Aalborg, Denmark.
Arch Toxicol ; 91(2): 799-810, 2017 Feb.
Article em En | MEDLINE | ID: mdl-26965496

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Testes de Toxicidade / Doença Hepática Induzida por Substâncias e Drogas / Cetoconazol Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Testes de Toxicidade / Doença Hepática Induzida por Substâncias e Drogas / Cetoconazol Idioma: En Ano de publicação: 2017 Tipo de documento: Article