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Rosiglitazone activation of PPARγ-dependent pathways is neuroprotective in human neural stem cells against amyloid-beta-induced mitochondrial dysfunction and oxidative stress.
Chiang, Ming-Chang; Nicol, Christopher J; Cheng, Yi-Chuan; Lin, Kuan-Hung; Yen, Chia-Hui; Lin, Chien-Hung.
Afiliação
  • Chiang MC; Department of Life Science, College of Science and Engineering, Fu Jen Catholic University, New Taipei City, Taiwan. Electronic address: cmcphd@gmail.com.
  • Nicol CJ; Division of Cancer Biology & Genetics, Departments of Pathology & Molecular Medicine and Biomedical & Molecular Sciences, Cancer Research Institute, Queen's University, Kingston, Ontario, Canada.
  • Cheng YC; Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Tao Yuan, Taiwan.
  • Lin KH; Graduate Institute of Biotechnology, Chinese Culture University, Taipei, Taiwan.
  • Yen CH; Department of International Business, Ming Chuan University, Taipei, Taiwan.
  • Lin CH; Department of Pediatrics, Taipei City Hospital Zhongxing Branch, Taipei, Taiwan.
Neurobiol Aging ; 40: 181-190, 2016 Apr.
Article em En | MEDLINE | ID: mdl-26973118
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Peptídeos beta-Amiloides / Estresse Oxidativo / Fármacos Neuroprotetores / Doenças Mitocondriais / Tiazolidinedionas / PPAR gama / Células-Tronco Neurais Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Peptídeos beta-Amiloides / Estresse Oxidativo / Fármacos Neuroprotetores / Doenças Mitocondriais / Tiazolidinedionas / PPAR gama / Células-Tronco Neurais Idioma: En Ano de publicação: 2016 Tipo de documento: Article