Shear Wave Elastography and Cervical Lymph Nodes: Predicting Malignancy.
Ultrasound Med Biol
; 42(6): 1273-81, 2016 06.
Article
em En
| MEDLINE
| ID: mdl-26976785
ABSTRACT
This prospective study evaluates the accuracy of virtual touch imaging quantification (VTIQ), a non-invasive shear wave elastography method for measuring cervical lymph nodes (LN) stiffness in differentiating benign from malignant LN. The study evaluated 270 LN in 236 patients with both conventional B-mode ultrasound and VTIQ shear wave elastography before fine-needle aspiration biopsy (FNAB). LN stiffness was measured as shear wave velocity (SWV) in m/s. Surgical resection was advised for FNAB results that were not clearly benign. Surgical pathology confirmed 54 malignant LN. The receiver operating curve (ROC) identified a single cut-off value of 2.93 m/s as the maximum SWV for predicting a malignant cervical LN. The sensitivity and specificity were 92.59% and 75.46%, respectively. Positive predictive value (PPV) was 48.54% and negative predictive value (NPV) was 97.60%. LN stiffness measured by VTIQ-generated shear wave elastography is an independent predictor of malignancy.
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Glândula Tireoide
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Técnicas de Imagem por Elasticidade
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Linfonodos
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article