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Copper complexes based on chiral Schiff-base ligands: DNA/BSA binding ability, DNA cleavage activity, cytotoxicity and mechanism of apoptosis.
Zhou, Xue-Quan; Li, Yang; Zhang, Dong-Yan; Nie, Yan; Li, Zong-Jin; Gu, Wen; Liu, Xin; Tian, Jin-Lei; Yan, Shi-Ping.
Afiliação
  • Zhou XQ; Department of Chemistry, Nankai University, Tianjin 300071, PR China; Key Laboratory of Advanced Energy Materials Chemistry (MOE), Nankai University, PR China.
  • Li Y; Medical School of Nankai University, PR China.
  • Zhang DY; Department of Chemistry, Nankai University, Tianjin 300071, PR China; Key Laboratory of Advanced Energy Materials Chemistry (MOE), Nankai University, PR China.
  • Nie Y; Medical School of Nankai University, PR China.
  • Li ZJ; Medical School of Nankai University, PR China.
  • Gu W; Department of Chemistry, Nankai University, Tianjin 300071, PR China; Key Laboratory of Advanced Energy Materials Chemistry (MOE), Nankai University, PR China.
  • Liu X; Department of Chemistry, Nankai University, Tianjin 300071, PR China; Key Laboratory of Advanced Energy Materials Chemistry (MOE), Nankai University, PR China.
  • Tian JL; Department of Chemistry, Nankai University, Tianjin 300071, PR China; Key Laboratory of Advanced Energy Materials Chemistry (MOE), Nankai University, PR China. Electronic address: tiant@nankai.edu.cn.
  • Yan SP; Department of Chemistry, Nankai University, Tianjin 300071, PR China; Key Laboratory of Advanced Energy Materials Chemistry (MOE), Nankai University, PR China.
Eur J Med Chem ; 114: 244-56, 2016 May 23.
Article em En | MEDLINE | ID: mdl-26994692
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos Organometálicos / Bases de Schiff / DNA / Soroalbumina Bovina / Apoptose / Cobre / Antineoplásicos Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos Organometálicos / Bases de Schiff / DNA / Soroalbumina Bovina / Apoptose / Cobre / Antineoplásicos Idioma: En Ano de publicação: 2016 Tipo de documento: Article