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The utility of stable isotope labeled (SIL) analogues in the bioanalysis of endogenous compounds by LC-MS applied to the study of bile acids in a metabolomics assay.
Zheng, Joanna J; Shields, Eric E; Snow, Kimberly J; Nelson, David M; Olah, Timothy V; Reily, Michael D; Robertson, Donald G; Shipkova, Petia A; Stryker, Steven A; Xin, Baomin; Drexler, Dieter M.
Afiliação
  • Zheng JJ; Bioanalytical Research, Bristol-Myers Squibb, Pennington, NJ 08534, USA.
  • Shields EE; Bioanalytical Research, Bristol-Myers Squibb, Wallingford, CT 06492, USA.
  • Snow KJ; Bioanalytical Research, Bristol-Myers Squibb, Wallingford, CT 06492, USA.
  • Nelson DM; Discovery Toxicology, Bristol-Myers Squibb, Princeton, NJ 08543, USA; Applied and Investigational Metabolomics, Bristol-Myers Squibb, Princeton, NJ 08543, USA.
  • Olah TV; Bioanalytical Research, Bristol-Myers Squibb, Princeton, NJ 08543, USA.
  • Reily MD; Applied and Investigational Metabolomics, Bristol-Myers Squibb, Princeton, NJ 08543, USA.
  • Robertson DG; Discovery Toxicology, Bristol-Myers Squibb, Princeton, NJ 08543, USA; Applied and Investigational Metabolomics, Bristol-Myers Squibb, Princeton, NJ 08543, USA.
  • Shipkova PA; Bioanalytical Research, Bristol-Myers Squibb, Wallingford, CT 06492, USA; Applied and Investigational Metabolomics, Bristol-Myers Squibb, Princeton, NJ 08543, USA.
  • Stryker SA; Discovery Toxicology, Bristol-Myers Squibb, Princeton, NJ 08543, USA; Applied and Investigational Metabolomics, Bristol-Myers Squibb, Princeton, NJ 08543, USA.
  • Xin B; Bioanalytical Research, Bristol-Myers Squibb, Pennington, NJ 08534, USA.
  • Drexler DM; Bioanalytical Research, Bristol-Myers Squibb, Wallingford, CT 06492, USA. Electronic address: dieter.drexler@bms.com.
Anal Biochem ; 503: 71-8, 2016 06 15.
Article em En | MEDLINE | ID: mdl-27033006
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácidos e Sais Biliares / Metabolômica / Marcação por Isótopo Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácidos e Sais Biliares / Metabolômica / Marcação por Isótopo Idioma: En Ano de publicação: 2016 Tipo de documento: Article