Beyond canonical: The Wnt and ß-catenin story.

Moon, Randall T; Gough, Nancy R

Moon, Randall T; Gough, Nancy R.

Afiliação

Moon RT; Board member, Science Signaling, AAAS, Washington, DC 20005, USA. Institute for Stem Cell and Regenerative Medicine, Howard Hughes Medical Institute, Department of Pharmacology, University of Washington School of Medicine, Seattle, WA 98109, USA.
Gough NR; Editor, Science Signaling, AAAS, Washington, DC 20005, USA. ngough@aaas.org.

Sci Signal ; 9(422): eg5, 2016 Apr 05.

Article em En | MEDLINE | ID: mdl-27048563

ABSTRACT

ABSTRACT

This Editorial Guide uses Wnt-stimulated activation of the transcriptional activity of ß-catenin, the canonical Wnt/ß-catenin pathway, to illustrate the hazards of limiting research investigation and questions to those that fit the "canonical" view.

Assuntos

Ativação Transcricional; Via de Sinalização Wnt; beta Catenina/metabolismo; Humanos; Publicações Periódicas como Assunto

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ativação Transcricional / Beta Catenina / Via de Sinalização Wnt Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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