Rapid parallel acquisition of somatic mutations after NPM1 in acute myeloid leukaemia evolution.

Grove, Carolyn S; Bolli, Niccolo; Manes, Nicla; Varela, Ignacio; Van't Veer, Mars; Bench, Anthony; Eldaly, Hesham; Wedge, David; Van Loo, Peter; Vassiliou, George S

Grove, Carolyn S; Bolli, Niccolo; Manes, Nicla; Varela, Ignacio; Van't Veer, Mars; Bench, Anthony; Eldaly, Hesham; Wedge, David; Van Loo, Peter; Vassiliou, George S.

Afiliação

Grove CS; Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, UK.
Bolli N; Department of Haematology, PathWest/Sir Charles Gairdner Hospital, Perth, Western Australia.
Manes N; Pathology and Laboratory Medicine, University of Western Australia, Perth, Australia.
Varela I; Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, UK.
Van't Veer M; Department of Haematology, University of Cambridge, Cambridge, UK.
Bench A; Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, UK.
Eldaly H; Institute of Biomedicine and Biotechnology of Cantabria, Cantabria, Spain.
Wedge D; Department of Haematology, Addenbrooke's Hospital, Cambridge, UK.
Van Loo P; Department of Haematology, Addenbrooke's Hospital, Cambridge, UK.
Vassiliou GS; Department of Haematology, Addenbrooke's Hospital, Cambridge, UK.

Br J Haematol ; 176(5): 825-829, 2017 03.

Article em En | MEDLINE | ID: mdl-27062498

Assuntos

Proteínas Nucleares/genética; Feminino; Humanos; Leucemia Mieloide Aguda/genética; Pessoa de Meia-Idade; Mutação; Proteínas Nucleares/metabolismo; Nucleofosmina

Palavras-chave

NPM1; acute myeloid leukaemia; chronic myelomonocytic leukaemia; clonal evolution; sequencing

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Nucleares Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Nucleares Idioma: En Ano de publicação: 2017 Tipo de documento: Article