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The role of CYP 3A4 and 1A1 in amiodarone-induced hepatocellular toxicity.
Wu, Qiangen; Ning, Baitang; Xuan, Jiekun; Ren, Zhen; Guo, Lei; Bryant, Matthew S.
Afiliação
  • Wu Q; Division of Biochemical Toxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA.
  • Ning B; Division of System Biology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA.
  • Xuan J; Division of Biochemical Toxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA.
  • Ren Z; Division of Biochemical Toxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA.
  • Guo L; Division of Biochemical Toxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA. Electronic address: Lei.Guo@fda.hhs.gov.
  • Bryant MS; Division of Biochemical Toxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA. Electronic address: Matthew.Bryant@fda.hhs.gov.
Toxicol Lett ; 253: 55-62, 2016 Jun 24.
Article em En | MEDLINE | ID: mdl-27113703
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Citocromo P-450 CYP1A1 / Hepatócitos / Citocromo P-450 CYP3A / Doença Hepática Induzida por Substâncias e Drogas / Amiodarona / Antiarrítmicos Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Citocromo P-450 CYP1A1 / Hepatócitos / Citocromo P-450 CYP3A / Doença Hepática Induzida por Substâncias e Drogas / Amiodarona / Antiarrítmicos Idioma: En Ano de publicação: 2016 Tipo de documento: Article