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PARP activity in peripheral blood lymphocytes as a predictive biomarker for PARP inhibition in tumor tissues - A population pharmacokinetic/pharmacodynamic analysis of rucaparib.
Wang, Diane D; Li, Chunze; Sun, Wan; Zhang, Shuzhong; Shalinsky, David R; Kern, Kenneth A; Curtin, Nicola J; Sam, Wai-Johnn; Kirkpatrick, Tanya R; Plummer, Ruth.
Afiliação
  • Wang DD; Pfizer Inc., San Diego, CA, USA.
  • Li C; Pfizer Inc., San Diego, CA, USA.
  • Sun W; Pfizer Inc., San Diego, CA, USA.
  • Zhang S; Pfizer Inc., San Diego, CA, USA.
  • Shalinsky DR; Pfizer Inc., San Diego, CA, USA.
  • Kern KA; Pfizer Inc., San Diego, CA, USA.
  • Curtin NJ; Northern Institute for Cancer Research, Medical School, Newcastle University, Newcastle Upon Tyne, UK.
  • Sam WJ; Pfizer Inc., San Diego, CA, USA.
  • Kirkpatrick TR; Pfizer Inc., San Diego, CA, USA.
  • Plummer R; Northern Institute for Cancer Research, Medical School, Newcastle University, Newcastle Upon Tyne, UK.
Clin Pharmacol Drug Dev ; 4(2): 89-98, 2015 03.
Article em En | MEDLINE | ID: mdl-27128213
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos / Poli(ADP-Ribose) Polimerases / Inibidores de Poli(ADP-Ribose) Polimerases / Indóis / Neoplasias Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos / Poli(ADP-Ribose) Polimerases / Inibidores de Poli(ADP-Ribose) Polimerases / Indóis / Neoplasias Idioma: En Ano de publicação: 2015 Tipo de documento: Article