Walker-A Motif Acts to Coordinate ATP Hydrolysis with Motor Output in Viral DNA Packaging.

delToro, Damian; Ortiz, David; Ordyan, Mariam; Sippy, Jean; Oh, Choon-Seok; Keller, Nicholas; Feiss, Michael; Catalano, Carlos E; Smith, Douglas E

delToro, Damian; Ortiz, David; Ordyan, Mariam; Sippy, Jean; Oh, Choon-Seok; Keller, Nicholas; Feiss, Michael; Catalano, Carlos E; Smith, Douglas E.

Afiliação

delToro D; Department of Physics, University of California, San Diego, La Jolla, CA 92093, USA.
Ortiz D; Department of Medicinal Chemistry, University of Washington, Seattle, WA 98195, USA.
Ordyan M; Department of Physics, University of California, San Diego, La Jolla, CA 92093, USA.
Sippy J; Department of Microbiology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
Oh CS; Department of Microbiology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
Keller N; Department of Physics, University of California, San Diego, La Jolla, CA 92093, USA.
Feiss M; Department of Microbiology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA. Electronic address: michael-feiss@uiowa.edu.
Catalano CE; Department of Medicinal Chemistry, University of Washington, Seattle, WA 98195, USA. Electronic address: carlos.catalano@ucdenver.edu.
Smith DE; Department of Physics, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address: des@ucsd.edu.

J Mol Biol ; 428(13): 2709-29, 2016 07 03.

Article em En | MEDLINE | ID: mdl-27139643

Assuntos

Trifosfato de Adenosina/metabolismo; Empacotamento do DNA/genética; DNA Viral/genética; Montagem de Vírus/genética; Adenosina Trifosfatases/metabolismo; Bacteriófago lambda/genética; Sítios de Ligação/genética; Hidrólise; Modelos Moleculares; Mutação Puntual/genética; Domínios Proteicos/genética; Proteínas Virais/metabolismo

Palavras-chave

ATPase; Optical tweezers; mutagenesis of Walker-A motif; terminase; viral DNA packaging motor

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA Viral / Trifosfato de Adenosina / Montagem de Vírus / Empacotamento do DNA Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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