Myofibril growth during cardiac hypertrophy is regulated through dual phosphorylation and acetylation of the actin capping protein CapZ.

Lin, Ying-Hsi; Warren, Chad M; Li, Jieli; McKinsey, Timothy A; Russell, Brenda

Lin, Ying-Hsi; Warren, Chad M; Li, Jieli; McKinsey, Timothy A; Russell, Brenda.

Afiliação

Lin YH; Department of Physiology and Biophysics, University of Illinois at Chicago, College of Medicine, Chicago, IL 60612-7342, United States; Department of Physiology & Biophysics, Center for Cardiovascular Research, University of Illinois at Chicago, Chicago, IL 60612-7342, United States.
Warren CM; Department of Physiology and Biophysics, University of Illinois at Chicago, College of Medicine, Chicago, IL 60612-7342, United States; Department of Physiology & Biophysics, Center for Cardiovascular Research, University of Illinois at Chicago, Chicago, IL 60612-7342, United States.
Li J; Department of Physiology and Biophysics, University of Illinois at Chicago, College of Medicine, Chicago, IL 60612-7342, United States; Department of Physiology & Biophysics, Center for Cardiovascular Research, University of Illinois at Chicago, Chicago, IL 60612-7342, United States.
McKinsey TA; Department of Medicine, Division of Cardiology and Center for Fibrosis Research and Translation, University of Colorado Anschutz Medical Campus, Aurora, CO 80045-0508, United States.
Russell B; Department of Physiology and Biophysics, University of Illinois at Chicago, College of Medicine, Chicago, IL 60612-7342, United States; Department of Physiology & Biophysics, Center for Cardiovascular Research, University of Illinois at Chicago, Chicago, IL 60612-7342, United States. Electronic

Cell Signal ; 28(8): 1015-24, 2016 08.

Article em En | MEDLINE | ID: mdl-27185186

Assuntos

Proteína de Capeamento de Actina CapZ/metabolismo; Cardiomegalia/metabolismo; Miofibrilas/metabolismo; Acetilação/efeitos dos fármacos; Actinas/metabolismo; Sequência de Aminoácidos; Animais; Animais Recém-Nascidos; Proteína de Capeamento de Actina CapZ/química; Cardiomegalia/patologia; Tamanho Celular/efeitos dos fármacos; Ventrículos do Coração/patologia; Inibidores de Histona Desacetilases/farmacologia; Histona Desacetilases/metabolismo; Modelos Biológicos; Miócitos Cardíacos/efeitos dos fármacos; Miócitos Cardíacos/metabolismo; Miofibrilas/efeitos dos fármacos; Fenilefrina/farmacologia; Fosforilação/efeitos dos fármacos; Proteína Quinase C-épsilon/metabolismo; Processamento de Proteína Pós-Traducional/efeitos dos fármacos; Ratos Sprague-Dawley; Sarcômeros/efeitos dos fármacos; Sarcômeros/metabolismo

Palavras-chave

Actin assembly; Mechanotransduction; Proteomics; Sarcomere; Signaling pathways

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cardiomegalia / Proteína de Capeamento de Actina CapZ / Miofibrilas Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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