Activation of the Caenorhabditis elegans Degenerin Channel by Shear Stress Requires the MEC-10 Subunit.

Shi, Shujie; Luke, Cliff J; Miedel, Mark T; Silverman, Gary A; Kleyman, Thomas R

Shi, Shujie; Luke, Cliff J; Miedel, Mark T; Silverman, Gary A; Kleyman, Thomas R.

Afiliação

Shi S; Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261.
Luke CJ; Department of Pediatrics, University of Pittsburgh, Pittsburgh, Pennsylvania 15261.
Miedel MT; Department of Pediatrics, University of Pittsburgh, Pittsburgh, Pennsylvania 15261.
Silverman GA; Department of Pediatrics, University of Pittsburgh, Pittsburgh, Pennsylvania 15261; Department of Cell Biology, University of Pittsburgh, Pittsburgh, Pennsylvania 15261.
Kleyman TR; Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261; Department of Cell Biology, University of Pittsburgh, Pittsburgh, Pennsylvania 15261; Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania 15261. Electronic address: kleyman@pitt.edu.

J Biol Chem ; 291(27): 14012-14022, 2016 Jul 01.

Article em En | MEDLINE | ID: mdl-27189943

Assuntos

Proteínas de Caenorhabditis elegans/metabolismo; Caenorhabditis elegans/metabolismo; Proteínas de Membrana/metabolismo; Estresse Mecânico; Animais; Proteínas de Caenorhabditis elegans/química; Proteínas de Caenorhabditis elegans/genética; Proteínas de Membrana/química; Proteínas de Membrana/genética; Mutagênese Sítio-Dirigida; Xenopus

Palavras-chave

Caenorhabditis elegans (C. elegans); acid-sensing ion channel (ASIC); electrophysiology; epithelial sodium channel (ENaC); mechanotransduction; shear stress

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estresse Mecânico / Caenorhabditis elegans / Proteínas de Caenorhabditis elegans / Proteínas de Membrana Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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