A preliminary feasibility study: Narrow-band imaging targeted versus standard white light endoscopy non-targeted biopsies in a surveillance Barrett's population.
Dig Liver Dis
; 48(9): 1048-53, 2016 Sep.
Article
em En
| MEDLINE
| ID: mdl-27246796
ABSTRACT
BACKGROUND:
Narrow band imaging (NBI) is used in the detection of intestinal metaplasia (IM) and dysplasia in patients with Barrett's oesophagus (BE).AIMS:
The study compared the usefulness of NBI with white-light standard endoscopy (WLSE) for the detection of dysplasia and IM in BE and determined the prediction of the histological diagnosis according to the mucosal and vascular patterns obtained by NBI. PATIENTS ANDMETHODS:
A total of 84 patients were prospectively enrolled in the study. Every patient underwent a WLSE with random biopsies and after 4-6 weeks, a NBI examination was performed.RESULTS:
NBI detected significant more IM positive biopsies than WLSE (74.5% vs. 35.9%; p<0.0001) and significant more patients with low grade dysplasia (LGD) (7.1% vs. 0%; p=0.03). Taking biopsy samples from the villous pattern determined the diagnosis of IM (80%) and biopsies from the area covered by the irregular pattern lead to the identification of LGD in 45.4% of the cases and indefinite dysplasia (ID) in 18.2% of the cases.CONCLUSION:
A thorough analysis of NBI patterns may lead to real-time IM diagnosis in the absence of the histological examination and may require targeted biopsies from the areas with an irregular pattern for diagnosing dysplasia.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Esôfago de Barrett
/
Esofagoscopia
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Imagem de Banda Estreita
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Intestinos
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article