Histones Induce the Procoagulant Phenotype of Endothelial Cells through Tissue Factor Up-Regulation and Thrombomodulin Down-Regulation.

Kim, Ji Eun; Yoo, Hyun Ju; Gu, Ja Yoon; Kim, Hyun Kyung

Kim, Ji Eun; Yoo, Hyun Ju; Gu, Ja Yoon; Kim, Hyun Kyung.

Afiliação

Kim JE; Department of Hemato-oncology, Healthcare Innovation Park, Seoul National University Bundang Hospital, Gyeonggi-do, South Korea.
Yoo HJ; Department of Laboratory Medicine and Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea.
Gu JY; Department of Laboratory Medicine and Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea.
Kim HK; Department of Laboratory Medicine and Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea.

PLoS One ; 11(6): e0156763, 2016.

Article em En | MEDLINE | ID: mdl-27258428

Assuntos

Células Endoteliais/metabolismo; Histonas/metabolismo; Trombomodulina/metabolismo; Tromboplastina/metabolismo; Linhagem Celular; Ensaio de Imunoadsorção Enzimática; Citometria de Fluxo; Humanos; Fosfatidilserinas/metabolismo; Isomerases de Dissulfetos de Proteínas/metabolismo; RNA Mensageiro/genética; Reação em Cadeia da Polimerase Via Transcriptase Reversa; Trombomodulina/genética; Tromboplastina/genética; Receptor 2 Toll-Like/metabolismo; Receptor 4 Toll-Like/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tromboplastina / Histonas / Trombomodulina / Células Endoteliais Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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