Phosphorylation of CMG helicase and Tof1 is required for programmed fork arrest.

Bastia, Deepak; Srivastava, Pankaj; Zaman, Shamsu; Choudhury, Malay; Mohanty, Bidyut K; Bacal, Julien; Langston, Lance D; Pasero, Philippe; O'Donnell, Michael E

Bastia, Deepak; Srivastava, Pankaj; Zaman, Shamsu; Choudhury, Malay; Mohanty, Bidyut K; Bacal, Julien; Langston, Lance D; Pasero, Philippe; O'Donnell, Michael E.

Afiliação

Bastia D; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC 29415; bastia@musc.edu odonnel@rockefeller.edu.
Srivastava P; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC 29415;
Zaman S; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC 29415;
Choudhury M; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC 29415;
Mohanty BK; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC 29415;
Bacal J; Institute of Human Genetics, Union Populaire Républicaine 1142, CNRS, 34396 Montpellier, France;
Langston LD; Howard Hughes Medical Institute, Rockefeller University, New York, NY 10065; Laboratory of DNA Replication, Rockefeller University, New York, NY 10065.
Pasero P; Institute of Human Genetics, Union Populaire Républicaine 1142, CNRS, 34396 Montpellier, France;
O'Donnell ME; Howard Hughes Medical Institute, Rockefeller University, New York, NY 10065; Laboratory of DNA Replication, Rockefeller University, New York, NY 10065 bastia@musc.edu odonnel@rockefeller.edu.

Proc Natl Acad Sci U S A ; 113(26): E3639-48, 2016 06 28.

Article em En | MEDLINE | ID: mdl-27298353

Assuntos

DNA Helicases/metabolismo; Replicação do DNA; Proteínas de Ligação a DNA/metabolismo; Proteínas de Saccharomyces cerevisiae/metabolismo; Saccharomyces cerevisiae/genética; Saccharomyces cerevisiae/metabolismo; Proteínas de Ciclo Celular/genética; Proteínas de Ciclo Celular/metabolismo; DNA Helicases/genética; Proteínas de Ligação a DNA/genética; Fosforilação; Proteínas Serina-Treonina Quinases/genética; Proteínas Serina-Treonina Quinases/metabolismo; Saccharomyces cerevisiae/enzimologia; Proteínas de Saccharomyces cerevisiae/genética

Palavras-chave

DDK; Fob1; Ter; Tof1; programmed fork arrest

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Saccharomyces cerevisiae / DNA Helicases / Proteínas de Saccharomyces cerevisiae / Proteínas de Ligação a DNA / Replicação do DNA Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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