Unusual serological findings associated with ceftriaxone-induced immune hemolytic anemia in a child with disseminated low-grade glioma.
Pediatr Blood Cancer
; 63(10): 1852-5, 2016 10.
Article
em En
| MEDLINE
| ID: mdl-27304608
ABSTRACT
Ceftriaxone-induced immune hemolytic anemia (CIHA) is the second most common cause of drug-induced hemolytic anemia. Prompt recognition of this drug reaction is essential because brisk hemolysis can be deadly. The extent to which ceftriaxone antibodies persist after CIHA is unknown; rechallenging patients who have experienced CIHA is not recommended. We report a case of CIHA in a neurooncology patient, which is the first to show anticeftriaxone antibodies with Rh specificity and persisted for 8 months after the drug reaction. These findings have implications for understanding the mechanism of CIHA.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Encefálicas
/
Ceftriaxona
/
Glioma
/
Anemia Hemolítica Autoimune
/
Antibacterianos
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article