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MultiQC: summarize analysis results for multiple tools and samples in a single report.
Ewels, Philip; Magnusson, Måns; Lundin, Sverker; Käller, Max.
Afiliação
  • Ewels P; Department of Biochemistry and Biophysics, Science for Life Laboratory, Stockholm University, Stockholm 106 91, Sweden.
  • Magnusson M; Department of Molecular Medicine and Surgery, Science for Life Laboratory, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.
  • Lundin S; Science for Life Laboratory, School of Biotechnology, Division of Gene Technology, Royal Institute of Technology, Stockholm, Sweden.
  • Käller M; Science for Life Laboratory, School of Biotechnology, Division of Gene Technology, Royal Institute of Technology, Stockholm, Sweden.
Bioinformatics ; 32(19): 3047-8, 2016 10 01.
Article em En | MEDLINE | ID: mdl-27312411
ABSTRACT
MOTIVATION Fast and accurate quality control is essential for studies involving next-generation sequencing data. Whilst numerous tools exist to quantify QC metrics, there is no common approach to flexibly integrate these across tools and large sample sets. Assessing analysis results across an entire project can be time consuming and error prone; batch effects and outlier samples can easily be missed in the early stages of analysis.

RESULTS:

We present MultiQC, a tool to create a single report visualising output from multiple tools across many samples, enabling global trends and biases to be quickly identified. MultiQC can plot data from many common bioinformatics tools and is built to allow easy extension and customization. AVAILABILITY AND IMPLEMENTATION MultiQC is available with an GNU GPLv3 license on GitHub, the Python Package Index and Bioconda. Documentation and example reports are available at http//multiqc.info CONTACT phil.ewels@scilifelab.se.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Controle de Qualidade / Sequenciamento de Nucleotídeos em Larga Escala Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Controle de Qualidade / Sequenciamento de Nucleotídeos em Larga Escala Idioma: En Ano de publicação: 2016 Tipo de documento: Article