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T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4⁺ T cells.
Arbore, Giuseppina; West, Erin E; Spolski, Rosanne; Robertson, Avril A B; Klos, Andreas; Rheinheimer, Claudia; Dutow, Pavel; Woodruff, Trent M; Yu, Zu Xi; O'Neill, Luke A; Coll, Rebecca C; Sher, Alan; Leonard, Warren J; Köhl, Jörg; Monk, Pete; Cooper, Matthew A; Arno, Matthew; Afzali, Behdad; Lachmann, Helen J; Cope, Andrew P; Mayer-Barber, Katrin D; Kemper, Claudia.
Afiliação
  • Arbore G; MRC Centre for Transplantation, Division of Transplant Immunology and Mucosal Biology, King's College London, London SE1 9RT, UK.
  • West EE; Laboratory of Molecular Immunology and Immunology Center, National Heart, Lung, and Blood Institute, Bethesda, MD 20892, USA.
  • Spolski R; Laboratory of Molecular Immunology and Immunology Center, National Heart, Lung, and Blood Institute, Bethesda, MD 20892, USA.
  • Robertson AAB; Institute for Molecular Bioscience and School of Biomedical Sciences, University of Queensland, QLD 4072, Australia.
  • Klos A; Institute for Medical Microbiology and Hospital Epidemiology, Medizinische Hochschule Hannover, 30625 Hannover, Germany.
  • Rheinheimer C; Institute for Medical Microbiology and Hospital Epidemiology, Medizinische Hochschule Hannover, 30625 Hannover, Germany.
  • Dutow P; Institute for Medical Microbiology and Hospital Epidemiology, Medizinische Hochschule Hannover, 30625 Hannover, Germany.
  • Woodruff TM; Institute for Molecular Bioscience and School of Biomedical Sciences, University of Queensland, QLD 4072, Australia.
  • Yu ZX; Pathology Core, National Heart, Lung, and Blood Institute, Bethesda, MD 20892, USA.
  • O'Neill LA; School of Biochemistry and Immunology, Trinity College Dublin, Dublin, Ireland.
  • Coll RC; Institute for Molecular Bioscience and School of Biomedical Sciences, University of Queensland, QLD 4072, Australia.
  • Sher A; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA.
  • Leonard WJ; Laboratory of Molecular Immunology and Immunology Center, National Heart, Lung, and Blood Institute, Bethesda, MD 20892, USA.
  • Köhl J; Institute for Systemic Inflammation Research, University of Lübeck, Lübeck, Germany.
  • Monk P; Division of Immunobiology, Cincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, OH, USA.
  • Cooper MA; Department of Infection and Immunity, University of Sheffield, Sheffield S10 2RX, UK.
  • Arno M; Institute for Molecular Bioscience and School of Biomedical Sciences, University of Queensland, QLD 4072, Australia.
  • Afzali B; Genomics Centre, Faculty of Life Sciences and Medicine, King's College London, London SE1 9NH, UK.
  • Lachmann HJ; MRC Centre for Transplantation, Division of Transplant Immunology and Mucosal Biology, King's College London, London SE1 9RT, UK.
  • Cope AP; Lymphocyte Cell Biology Section, Molecular Immunology and Inflammation Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD 20892, USA.
  • Mayer-Barber KD; UK National Amyloidosis Centre, Division of Medicine, University College London, Royal Free Campus, London NW3 2PF, UK.
  • Kemper C; Academic Department of Rheumatology, Division of Immunology, Infection and Inflammatory Diseases, King's College London, London SE1 1UL, UK.
Science ; 352(6292): aad1210, 2016 Jun 17.
Article em En | MEDLINE | ID: mdl-27313051
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos T CD4-Positivos / Proteínas de Transporte / Complemento C5a / Interferon gama / Células Th1 / Inflamassomos Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos T CD4-Positivos / Proteínas de Transporte / Complemento C5a / Interferon gama / Células Th1 / Inflamassomos Idioma: En Ano de publicação: 2016 Tipo de documento: Article