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PTP1B controls non-mitochondrial oxygen consumption by regulating RNF213 to promote tumour survival during hypoxia.
Banh, Robert S; Iorio, Caterina; Marcotte, Richard; Xu, Yang; Cojocari, Dan; Rahman, Anas Abdel; Pawling, Judy; Zhang, Wei; Sinha, Ankit; Rose, Christopher M; Isasa, Marta; Zhang, Shuang; Wu, Ronald; Virtanen, Carl; Hitomi, Toshiaki; Habu, Toshiyuki; Sidhu, Sachdev S; Koizumi, Akio; Wilkins, Sarah E; Kislinger, Thomas; Gygi, Steven P; Schofield, Christopher J; Dennis, James W; Wouters, Bradly G; Neel, Benjamin G.
Afiliação
  • Banh RS; Department of Medical Biophysics, University of Toronto, Toronto, ON, M5G 2M9, Canada.
  • Iorio C; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, M5G 1L7, Canada.
  • Marcotte R; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, M5G 1L7, Canada.
  • Xu Y; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, M5G 1L7, Canada.
  • Cojocari D; Department of Medical Biophysics, University of Toronto, Toronto, ON, M5G 2M9, Canada.
  • Rahman AA; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, M5G 1L7, Canada.
  • Pawling J; Department of Medical Biophysics, University of Toronto, Toronto, ON, M5G 2M9, Canada.
  • Zhang W; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, M5G 1L7, Canada.
  • Sinha A; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, M5G 1X5, Canada.
  • Rose CM; Department of Genetics, Research Center, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
  • Isasa M; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, M5G 1X5, Canada.
  • Zhang S; Donnelly Centre for Cellular and Biomolecular Research, Banting and Best Department of Medical Research, University of Toronto, Toronto, ON, M5S 3E1, Canada.
  • Wu R; Department of Medical Biophysics, University of Toronto, Toronto, ON, M5G 2M9, Canada.
  • Virtanen C; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, M5G 1L7, Canada.
  • Hitomi T; Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA.
  • Habu T; Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA.
  • Sidhu SS; Laura and Isaac Perlmutter Cancer Center, New York University Langone Medical Center, New York University, New York, NY 10016, USA.
  • Koizumi A; Department of Medical Biophysics, University of Toronto, Toronto, ON, M5G 2M9, Canada.
  • Wilkins SE; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, M5G 1L7, Canada.
  • Kislinger T; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, M5G 1L7, Canada.
  • Gygi SP; Department of Health and Environmental Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Schofield CJ; Department of Radiation System Biology, Institute of Radiation Biology Center, Kyoto University, Kyoto, Japan.
  • Dennis JW; Donnelly Centre for Cellular and Biomolecular Research, Banting and Best Department of Medical Research, University of Toronto, Toronto, ON, M5S 3E1, Canada.
  • Wouters BG; Department of Health and Environmental Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Neel BG; Chemistry Research Laboratory, Oxford University, 12 Mansfield Road, Oxford OX1 3TA, UK.
Nat Cell Biol ; 18(7): 803-813, 2016 07.
Article em En | MEDLINE | ID: mdl-27323329
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Consumo de Oxigênio / Adenosina Trifosfatases / Ubiquitina-Proteína Ligases / Proteína Tirosina Fosfatase não Receptora Tipo 1 Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Consumo de Oxigênio / Adenosina Trifosfatases / Ubiquitina-Proteína Ligases / Proteína Tirosina Fosfatase não Receptora Tipo 1 Idioma: En Ano de publicação: 2016 Tipo de documento: Article