One protein, multiple pathologies: multifaceted involvement of amyloid ß in neurodegenerative disorders of the brain and retina.

Gupta, Vivek; Gupta, Veer B; Chitranshi, Nitin; Gangoda, Sumudu; Vander Wall, Roshana; Abbasi, Mojdeh; Golzan, Mojtaba; Dheer, Yogita; Shah, Tejal; Avolio, Alberto; Chung, Roger; Martins, Ralph; Graham, Stuart

Gupta, Vivek; Gupta, Veer B; Chitranshi, Nitin; Gangoda, Sumudu; Vander Wall, Roshana; Abbasi, Mojdeh; Golzan, Mojtaba; Dheer, Yogita; Shah, Tejal; Avolio, Alberto; Chung, Roger; Martins, Ralph; Graham, Stuart.

Afiliação

Gupta V; Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia.
Gupta VB; School of Medical Sciences, Edith Cowan University, Perth, Australia. v.gupta@ecu.edu.au.
Chitranshi N; Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia.
Gangoda S; Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia.
Vander Wall R; Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia.
Abbasi M; Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia.
Golzan M; Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia.
Dheer Y; Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia.
Shah T; School of Medical Sciences, Edith Cowan University, Perth, Australia.
Avolio A; Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia.
Chung R; Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia.
Martins R; School of Medical Sciences, Edith Cowan University, Perth, Australia.
Graham S; Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia.

Cell Mol Life Sci ; 73(22): 4279-4297, 2016 11.

Article em En | MEDLINE | ID: mdl-27333888

Assuntos

Peptídeos beta-Amiloides/metabolismo; Encéfalo/patologia; Doenças Neurodegenerativas/metabolismo; Retina/patologia; Animais; Encéfalo/metabolismo; Humanos; Inflamação/patologia; Agregados Proteicos; Retina/metabolismo

Palavras-chave

Electroretinogram; Inflammation; Metal ions; Mitochondrial impairment; Neurotrophic factors; Optical coherence tomography; Oxidative stress; Protein aggregation; Vascular dysfunction

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Base de dados: MEDLINE Assunto principal: Retina / Encéfalo / Peptídeos beta-Amiloides / Doenças Neurodegenerativas Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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