The Ensembl gene annotation system.
Database (Oxford)
; 20162016.
Article
em En
| MEDLINE
| ID: mdl-27337980
ABSTRACT
The Ensembl gene annotation system has been used to annotate over 70 different vertebrate species across a wide range of genome projects. Furthermore, it generates the automatic alignment-based annotation for the human and mouse GENCODE gene sets. The system is based on the alignment of biological sequences, including cDNAs, proteins and RNA-seq reads, to the target genome in order to construct candidate transcript models. Careful assessment and filtering of these candidate transcripts ultimately leads to the final gene set, which is made available on the Ensembl website. Here, we describe the annotation process in detail.Database URL http//www.ensembl.org/index.html.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Internet
/
Bases de Dados de Ácidos Nucleicos
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Bases de Dados de Proteínas
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Anotação de Sequência Molecular
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article