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Histone modifications and p53 binding poise the p21 promoter for activation in human embryonic stem cells.
Itahana, Yoko; Zhang, Jinqiu; Göke, Jonathan; Vardy, Leah A; Han, Rachel; Iwamoto, Kozue; Cukuroglu, Engin; Robson, Paul; Pouladi, Mahmoud A; Colman, Alan; Itahana, Koji.
Afiliação
  • Itahana Y; Cancer &Stem Cell Biology Program, Duke-NUS Medical School, 8 College Road, 169857 Singapore.
  • Zhang J; Stem Cell Disease Models A*STAR Institute of Medical Biology, 8A Biomedical Grove, Immunos, 138648 Singapore.
  • Göke J; Stem Cell and Regenerative Biology, Genome Institute of Singapore, 60 Biopolis Street, Genome Building, 138672 Singapore.
  • Vardy LA; Translational Laboratory in Genetic Medicine, A*STAR, 8A Biomedical Grove, Immunos, 138648 Singapore.
  • Han R; Computational &Systems Biology Genome Building, 138672 Singapore.
  • Iwamoto K; Translational Regulation in Stem Cells, A*STAR Institute of Medical Biology, 8A Biomedical Grove, Immunos, 138648 Singapore.
  • Cukuroglu E; School of Biological Sciences, Nanyang Technological University, 637551 Singapore.
  • Robson P; Cancer &Stem Cell Biology Program, Duke-NUS Medical School, 8 College Road, 169857 Singapore.
  • Pouladi MA; Cancer &Stem Cell Biology Program, Duke-NUS Medical School, 8 College Road, 169857 Singapore.
  • Colman A; Computational &Systems Biology Genome Building, 138672 Singapore.
  • Itahana K; Stem Cell and Regenerative Biology, Genome Institute of Singapore, 60 Biopolis Street, Genome Building, 138672 Singapore.
Sci Rep ; 6: 28112, 2016 06 27.
Article em En | MEDLINE | ID: mdl-27346849
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Histonas / Proteína Supressora de Tumor p53 / Inibidor de Quinase Dependente de Ciclina p21 / Células-Tronco Embrionárias Humanas Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Histonas / Proteína Supressora de Tumor p53 / Inibidor de Quinase Dependente de Ciclina p21 / Células-Tronco Embrionárias Humanas Idioma: En Ano de publicação: 2016 Tipo de documento: Article