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HLA-A, -B, -C, -DRB1 and -DQB1 alleles and haplotypes in 951 Southeast Asia Malays from Peninsular Malaysia.
Tan, Lay-Kim; Mohd-Farid, Baharin; Salsabil, Sulaiman; Heselynn, Hussein; Wahinuddin, Sulaiman; Lau, Ing-Soo; Gun, Suk-Chyn; Nor-Suhaila, Sharil; Eashwary, M; Mohd-Shahrir, Mohamed Said; Ainon, Mohd-Mokhtar; Azmillah, Rosman; Muhaini, Othman; Shahnaz, Murad; Too, Chun-Lai.
Afiliação
  • Tan LK; Allergy and Immunology Research Center, Institute for Medical Research, Kuala Lumpur, Malaysia. Electronic address: tanlk@imr.gov.my.
  • Mohd-Farid B; Allergy and Immunology Research Center, Institute for Medical Research, Kuala Lumpur, Malaysia.
  • Salsabil S; Allergy and Immunology Research Center, Institute for Medical Research, Kuala Lumpur, Malaysia.
  • Heselynn H; Department of Medicine, Putrajaya Hospital, Wilayah Persekutuan Putrajaya, Malaysia.
  • Wahinuddin S; Department of Medicine, Hospital Raja Perempuan Bainun, Ipoh, Perak, Malaysia; Universiti Kuala Lumpur, Royal College of Medicine Perak, No 3, Jalan Greentown, 30450 Ipoh, Perak, Malaysia.
  • Lau IS; Department of Medicine, Hospital Selayang, Selangor, Malaysia.
  • Gun SC; Department of Medicine, Hospital Tunku Ja'afar Seremban, Negari Sembilan, Malaysia.
  • Nor-Suhaila S; Department of Medicine, Putrajaya Hospital, Wilayah Persekutuan Putrajaya, Malaysia.
  • Eashwary M; Department of Medicine, Putrajaya Hospital, Wilayah Persekutuan Putrajaya, Malaysia.
  • Mohd-Shahrir MS; Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Center, Selangor, Malaysia.
  • Ainon MM; Department of Medicine, Tengku Ampuan Afzan Hospital, Kuantan, Pahang, Malaysia.
  • Azmillah R; Department of Medicine, Hospital Selayang, Selangor, Malaysia.
  • Muhaini O; Department of Medicine, Hospital Raja Perempuan Bainun, Ipoh, Perak, Malaysia.
  • Shahnaz M; Allergy and Immunology Research Center, Institute for Medical Research, Kuala Lumpur, Malaysia.
  • Too CL; Allergy and Immunology Research Center, Institute for Medical Research, Kuala Lumpur, Malaysia; Rheumatology Unit, Department of Medicine, CMM L8:O4, Karolinska University Hospital and Karolinska Institutet, 17176 Stockholm, Sweden. Electronic address: toocl@imr.gov.my.
Hum Immunol ; 77(10): 818-819, 2016 Oct.
Article em En | MEDLINE | ID: mdl-27370684
ABSTRACT
A total of 951 Southeast Asia Malays from Peninsular Malaysia were genotyped for HLA-A, -B, -C -DRB1, and -DQB1 loci using polymerase chain reaction sequence-specific oligonucleotide probe hybridization methods. In this report, there were significant deviation from Hardy-Weinberg proportions for the HLA-A (p<0.0001), -B (p<0.0001), -DRB1 (p<0.0001) and -DQB1 (p<0.01) loci. Minor deviations from HWEP were detected for HLA-C (p=0.01). This genotype data was available in Allele Frequencies Network Database (AFND) Gonzalez-Galarza et al. (2015).
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antígenos HLA-A / Antígenos HLA-C / Etnicidade / Antígeno HLA-B27 / Cadeias beta de HLA-DQ / Cadeias HLA-DRB1 Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antígenos HLA-A / Antígenos HLA-C / Etnicidade / Antígeno HLA-B27 / Cadeias beta de HLA-DQ / Cadeias HLA-DRB1 Idioma: En Ano de publicação: 2016 Tipo de documento: Article