A case of refractory thrombotic thrombocytopenic purpura treated with plasmapheresis and rituximab.
S Afr Med J
; 106(7): 689-91, 2016 Jun 17.
Article
em En
| MEDLINE
| ID: mdl-27384362
ABSTRACT
Thrombotic thrombocytopenic purpura (TTP) is a rare, life-threatening disorder with no prevalence or incidence studies in sub-Saharan Africa. Acquired TTP has several causes, all of which lead to decreased activity of von Willebrand factor cleaving protease (ADAMTS13) due to autoantibodies that are directed towards ADAMTS13. We report a case of a 46-year-old man who presented with most of the classic clinical manifestations of TTP.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Púrpura Trombocitopênica Trombótica
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Plasmaferese
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Rituximab
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Fatores Imunológicos
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article