Impact of ABCB1 1236C > T-2677G > T-3435C > T polymorphisms on the anti-proliferative activity of imatinib, nilotinib, dasatinib and ponatinib.

Dessilly, Géraldine; Panin, Nadtha; Elens, Laure; Haufroid, Vincent; Demoulin, Jean-Baptiste

Dessilly, Géraldine; Panin, Nadtha; Elens, Laure; Haufroid, Vincent; Demoulin, Jean-Baptiste.

Afiliação

Dessilly G; Louvain centre for Toxicology and Applied Pharmacology, Institut de Recherche Expérimentale et Clinique, Université catholique de Louvain, Brussels, Belgium.
Panin N; Louvain centre for Toxicology and Applied Pharmacology, Institut de Recherche Expérimentale et Clinique, Université catholique de Louvain, Brussels, Belgium.
Elens L; Louvain Drug Research Institute, Université catholique de Louvain, Brussels, Belgium.
Haufroid V; Louvain centre for Toxicology and Applied Pharmacology, Institut de Recherche Expérimentale et Clinique, Université catholique de Louvain, Brussels, Belgium.
Demoulin JB; Department of Clinical Chemistry, Cliniques Universitaires Saint-Luc, Université catholique de Louvain, Brussels, Belgium.

Sci Rep ; 6: 29559, 2016 07 12.

Article em En | MEDLINE | ID: mdl-27405085

Assuntos

Antineoplásicos/farmacologia; Proliferação de Células/efeitos dos fármacos; Dasatinibe/farmacologia; Mesilato de Imatinib/farmacologia; Imidazóis/farmacologia; Inibidores de Proteínas Quinases/farmacologia; Piridazinas/farmacologia; Pirimidinas/farmacologia; Subfamília B de Transportador de Cassetes de Ligação de ATP/genética; Células HEK293; Humanos; Células K562; Polimorfismo de Nucleotídeo Único

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piridazinas / Pirimidinas / Inibidores de Proteínas Quinases / Proliferação de Células / Mesilato de Imatinib / Dasatinibe / Imidazóis / Antineoplásicos Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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