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Design and Characterization of Superpotent Bivalent Ligands Targeting Oxytocin Receptor Dimers via a Channel-Like Structure.
Busnelli, Marta; Kleinau, Gunnar; Muttenthaler, Markus; Stoev, Stoytcho; Manning, Maurice; Bibic, Lucka; Howell, Lesley A; McCormick, Peter J; Di Lascio, Simona; Braida, Daniela; Sala, Mariaelvina; Rovati, G Enrico; Bellini, Tommaso; Chini, Bice.
Afiliação
  • Busnelli M; CNR, Institute of Neuroscience , Milan, Italy 20129.
  • Kleinau G; Department of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano , Milan, Italy 20129.
  • Muttenthaler M; Institute of Experimental Pediatric Endocrinology, Charité-Universitätsmedizin Berlin , Berlin, Germany 13353.
  • Stoev S; Institute for Molecular Bioscience, The University of Queensland , Brisbane, Australia 4072.
  • Manning M; Department of Biochemistry and Cancer Biology, University of Toledo , Toledo, Ohio 43614, United States.
  • Bibic L; Department of Biochemistry and Cancer Biology, University of Toledo , Toledo, Ohio 43614, United States.
  • Howell LA; School of Pharmacy, University of East Anglia , Norwich Research Park, Norwich, U.K. NR4 7TJ.
  • McCormick PJ; School of Pharmacy, University of East Anglia , Norwich Research Park, Norwich, U.K. NR4 7TJ.
  • Di Lascio S; School of Pharmacy, University of East Anglia , Norwich Research Park, Norwich, U.K. NR4 7TJ.
  • Braida D; Department of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano , Milan, Italy 20129.
  • Sala M; Department of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano , Milan, Italy 20129.
  • Rovati GE; CNR, Institute of Neuroscience , Milan, Italy 20129.
  • Bellini T; Department of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano , Milan, Italy 20129.
  • Chini B; Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano , Milan, Italy 20133.
J Med Chem ; 59(15): 7152-66, 2016 08 11.
Article em En | MEDLINE | ID: mdl-27420737
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ocitocina / Desenho de Fármacos / Receptores de Ocitocina Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ocitocina / Desenho de Fármacos / Receptores de Ocitocina Idioma: En Ano de publicação: 2016 Tipo de documento: Article