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Inhibiting TLR2 activation attenuates amyloid accumulation and glial activation in a mouse model of Alzheimer's disease.
McDonald, Claire L; Hennessy, Edel; Rubio-Araiz, Ana; Keogh, Brian; McCormack, William; McGuirk, Peter; Reilly, Mary; Lynch, Marina A.
Afiliação
  • McDonald CL; Trinity College Institute for Neuroscience, Trinity College, Dublin 2, Ireland.
  • Hennessy E; Physical Therapy and Rehabilitation Science, Brain and Spinal Injury Center, University of California San Francisco, San Francisco General Hospital, 1001 Potrero av, Bld#1, Room#101, 94110 San Francisco, CA, United States.
  • Rubio-Araiz A; Trinity College Institute for Neuroscience, Trinity College, Dublin 2, Ireland.
  • Keogh B; Opsona Therapeutics LTD, 2nd Floor Ashford House, Tara Street, Dublin 2 D02 VX67, Ireland.
  • McCormack W; Immune Regulation Research Group, Trinity Biomedical Sciences Institute, Trinity College Dublin, 152-160 Pearse St, Dublin 2, Ireland.
  • McGuirk P; Opsona Therapeutics LTD, 2nd Floor Ashford House, Tara Street, Dublin 2 D02 VX67, Ireland.
  • Reilly M; Opsona Therapeutics LTD, 2nd Floor Ashford House, Tara Street, Dublin 2 D02 VX67, Ireland.
  • Lynch MA; Trinity College Institute for Neuroscience, Trinity College, Dublin 2, Ireland. Electronic address: lynchma@tcd.ie.
Brain Behav Immun ; 58: 191-200, 2016 Nov.
Article em En | MEDLINE | ID: mdl-27422717
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Astrócitos / Microglia / Placa Amiloide / Receptor 2 Toll-Like / Doença de Alzheimer Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Astrócitos / Microglia / Placa Amiloide / Receptor 2 Toll-Like / Doença de Alzheimer Idioma: En Ano de publicação: 2016 Tipo de documento: Article