Outgroups and Positive Selection: The Nothobranchius furzeri Case.

Sahm, Arne; Platzer, Matthias; Cellerino, Alessandro

Sahm, Arne; Platzer, Matthias; Cellerino, Alessandro.

Afiliação

Sahm A; Leibniz Institute on Aging, Fritz Lipmann Institute, Jena, Germany.
Platzer M; Leibniz Institute on Aging, Fritz Lipmann Institute, Jena, Germany.
Cellerino A; Leibniz Institute on Aging, Fritz Lipmann Institute, Jena, Germany; Laboratory of Biology Bio@SNS, Scuola Normale Superiore, Pisa, Italy. Electronic address: alessandro.cellerino@sns.it.

Trends Genet ; 32(9): 523-525, 2016 09.

Article em En | MEDLINE | ID: mdl-27423541

ABSTRACT

ABSTRACT

Applications of positive selection analysis increase with the number of species for which genome/transcriptome sequences become available. Using the recently sequenced turquoise killifish (Nothobranchius furzeri) genome as an example, we compare two different approaches based on different outgroup selection. The combination of these two methods allows the origin of positively selected sites in aging-related genes of the N. furzeri genome to be determined.

Assuntos

Fundulidae/genética; Filogenia; Seleção Genética/genética; Transcriptoma/genética; Animais; Genoma

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Filogenia / Seleção Genética / Fundulidae / Transcriptoma Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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