Characterization of Enzymes Catalyzing Transformations of Cysteine S-Conjugated Intermediates in the Lincosamide Biosynthetic Pathway.

Ushimaru, Richiro; Lin, Chia-I; Sasaki, Eita; Liu, Hung-Wen

Ushimaru, Richiro; Lin, Chia-I; Sasaki, Eita; Liu, Hung-Wen.

Afiliação

Ushimaru R; Division of Chemical Biology and Medicinal Chemistry, College of Pharmacy, Department of Chemistry, University of Texas at Austin, 1 University Station A1935, Austin, TX, 78712, USA.
Lin CI; Division of Chemical Biology and Medicinal Chemistry, College of Pharmacy, Department of Chemistry, University of Texas at Austin, 1 University Station A1935, Austin, TX, 78712, USA.
Sasaki E; Division of Chemical Biology and Medicinal Chemistry, College of Pharmacy, Department of Chemistry, University of Texas at Austin, 1 University Station A1935, Austin, TX, 78712, USA.
Liu HW; Division of Chemical Biology and Medicinal Chemistry, College of Pharmacy, Department of Chemistry, University of Texas at Austin, 1 University Station A1935, Austin, TX, 78712, USA. h.w.liu@mail.utexas.edu.

Chembiochem ; 17(17): 1606-11, 2016 09 02.

Article em En | MEDLINE | ID: mdl-27431934

Assuntos

Biocatálise; Cisteína/metabolismo; Lincosamidas/biossíntese; Metiltransferases/metabolismo; Vias Biossintéticas; Cisteína/química; Lincosamidas/química; Estrutura Molecular; Streptomyces/enzimologia

Palavras-chave

biosynthesis; catalytic mechanisms; enzymes; lincosamides; pyridoxal 5'-phosphate

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cisteína / Lincosamidas / Biocatálise / Metiltransferases Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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