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Rare allergic reaction of the kidney: sitagliptin-induced acute tubulointerstitial nephritis.
Alsaad, Ali A; Dhannoon, Sarah M; Pantin, Sally-Ann L; Porter, Ivan E.
Afiliação
  • Alsaad AA; Department of Internal Medicine, Mayo Clinic Florida, Jacksonville, Florida, USA.
  • Dhannoon SM; Department of Internal Medicine, University of Central Florida, Orlando, Florida, USA.
  • Pantin SA; Department of Family Medicine, Mayo Clinic, Jacksonville, Florida, USA.
  • Porter IE; Department of Nephrology, Mayo Clinic, Jacksonville, Florida, USA.
BMJ Case Rep ; 20162016 Jul 19.
Article em En | MEDLINE | ID: mdl-27436034
ABSTRACT
A 56-year-old man with a history of diabetes mellitus type-2 and stage-2 chronic kidney disease secondary to diabetic nephropathy presented with an acute deterioration of kidney function. Non-invasive work-up failed to reveal the underlying aetiology for the acute kidney failure. Kidney biopsy revealed acute tubulointerstitial nephritis (ATIN) which was attributed to sitagliptin use. Only few case reports have shown this correlation. Our aim is to alert physicians and other providers of the potential effect of sitagliptin to cause ATIN with this biopsy-proven case.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Diabetes Mellitus Tipo 2 / Hipersensibilidade a Drogas / Fosfato de Sitagliptina / Rim / Nefrite Intersticial Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Diabetes Mellitus Tipo 2 / Hipersensibilidade a Drogas / Fosfato de Sitagliptina / Rim / Nefrite Intersticial Idioma: En Ano de publicação: 2016 Tipo de documento: Article