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Combining genomewide association study and lung eQTL analysis provides evidence for novel genes associated with asthma.
Nieuwenhuis, M A; Siedlinski, M; van den Berge, M; Granell, R; Li, X; Niens, M; van der Vlies, P; Altmüller, J; Nürnberg, P; Kerkhof, M; van Schayck, O C; Riemersma, R A; van der Molen, T; de Monchy, J G; Bossé, Y; Sandford, A; Bruijnzeel-Koomen, C A; Gerth van Wijk, R; Ten Hacken, N H; Timens, W; Boezen, H M; Henderson, J; Kabesch, M; Vonk, J M; Postma, D S; Koppelman, G H.
Afiliação
  • Nieuwenhuis MA; Department of Pulmonary Diseases, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • Siedlinski M; Groningen Research Institute for Asthma and COPD (GRIAC), University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • van den Berge M; Groningen Research Institute for Asthma and COPD (GRIAC), University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • Granell R; Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • Li X; Department of Pulmonary Diseases, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • Niens M; Groningen Research Institute for Asthma and COPD (GRIAC), University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • van der Vlies P; School of Social and Community Medicine, University of Bristol, Bristol, UK.
  • Altmüller J; Wake Forest School of Medicine, Center for Genomics and Personalized Medicine Research and the Section on Pulmonary, Critical Care, Allergy and Immunologic Disease, Winston-Salem, NC, USA.
  • Nürnberg P; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • Kerkhof M; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • van Schayck OC; Cologne Center for Genomics (CCG), Universität zu Köln, Köln, Germany.
  • Riemersma RA; Cologne Center for Genomics (CCG), Universität zu Köln, Köln, Germany.
  • van der Molen T; Groningen Research Institute for Asthma and COPD (GRIAC), University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • de Monchy JG; Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • Bossé Y; Department of General Practice, CAPHRI, MUMC+, Maastricht, the Netherlands.
  • Sandford A; Groningen Research Institute for Asthma and COPD (GRIAC), University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • Bruijnzeel-Koomen CA; Department of General Practice, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • Gerth van Wijk R; Groningen Research Institute for Asthma and COPD (GRIAC), University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • Ten Hacken NH; Department of General Practice, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • Timens W; Groningen Research Institute for Asthma and COPD (GRIAC), University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • Boezen HM; Department Allergology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • Henderson J; Department of Molecular Medicine, Institut Universitaire de Cardiologie et de Pneumologie de Québec, Laval University, Québec, Canada.
  • Kabesch M; James Hogg Research Laboratory, St Paul's Hospital, The University of British Columbia, Vancouver, Canada.
  • Vonk JM; Department of Dermatology and Allergology, University Medical Center Utrecht, Utrecht, the Netherlands.
  • Postma DS; Department of Allergology, Erasmus Medical Centre Rotterdam, Rotterdam, the Netherlands.
  • Koppelman GH; Department of Pulmonary Diseases, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
Allergy ; 71(12): 1712-1720, 2016 12.
Article em En | MEDLINE | ID: mdl-27439200
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Asma / Predisposição Genética para Doença / Locos de Características Quantitativas / Estudo de Associação Genômica Ampla / Pulmão Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Asma / Predisposição Genética para Doença / Locos de Características Quantitativas / Estudo de Associação Genômica Ampla / Pulmão Idioma: En Ano de publicação: 2016 Tipo de documento: Article