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Multiple rare variants in high-risk pancreatic cancer-related genes may increase risk for pancreatic cancer in a subset of patients with and without germline CDKN2A mutations.
Yang, Xiaohong R; Rotunno, Melissa; Xiao, Yanzi; Ingvar, Christian; Helgadottir, Hildur; Pastorino, Lorenza; van Doorn, Remco; Bennett, Hunter; Graham, Cole; Sampson, Joshua N; Malasky, Michael; Vogt, Aurelie; Zhu, Bin; Bianchi-Scarra, Giovanna; Bruno, William; Queirolo, Paola; Fornarini, Giuseppe; Hansson, Johan; Tuominen, Rainer; Burdett, Laurie; Hicks, Belynda; Hutchinson, Amy; Jones, Kristine; Yeager, Meredith; Chanock, Stephen J; Landi, Maria Teresa; Höiom, Veronica; Olsson, Håkan; Gruis, Nelleke; Ghiorzo, Paola; Tucker, Margaret A; Goldstein, Alisa M.
Afiliação
  • Yang XR; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
  • Rotunno M; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
  • Xiao Y; Division of Cancer Control and Population Studies, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
  • Ingvar C; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
  • Helgadottir H; Department of Surgery, Lund University Hospital, Lund, Sweden.
  • Pastorino L; Department of Oncology Pathology, Karolinska Institutet and Karolinska University Hospital, Solna, Stockholm, Sweden.
  • van Doorn R; Department of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy.
  • Bennett H; Genetics of Rare Cancers, IRCCS AOU San Martino-IST, Genoa, Italy.
  • Graham C; Department of Dermatology, Leiden University Medical Center, Leiden, The Netherlands.
  • Sampson JN; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
  • Malasky M; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
  • Vogt A; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
  • Zhu B; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
  • Bianchi-Scarra G; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, MD, USA.
  • Bruno W; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
  • Queirolo P; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, MD, USA.
  • Fornarini G; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
  • Hansson J; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, MD, USA.
  • Tuominen R; Department of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy.
  • Burdett L; Genetics of Rare Cancers, IRCCS AOU San Martino-IST, Genoa, Italy.
  • Hicks B; Department of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy.
  • Hutchinson A; Genetics of Rare Cancers, IRCCS AOU San Martino-IST, Genoa, Italy.
  • Jones K; Medical Oncology Unit, IRCCS AOU San Martino-IST, Genoa, Italy.
  • Yeager M; Medical Oncology Unit, IRCCS AOU San Martino-IST, Genoa, Italy.
  • Chanock SJ; Department of Oncology Pathology, Karolinska Institutet and Karolinska University Hospital, Solna, Stockholm, Sweden.
  • Landi MT; Department of Oncology Pathology, Karolinska Institutet and Karolinska University Hospital, Solna, Stockholm, Sweden.
  • Höiom V; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
  • Olsson H; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, MD, USA.
  • Gruis N; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
  • Ghiorzo P; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, MD, USA.
  • Tucker MA; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
  • Goldstein AM; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, MD, USA.
Hum Genet ; 135(11): 1241-1249, 2016 Nov.
Article em En | MEDLINE | ID: mdl-27449771
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Inibidor de Quinase Dependente de Ciclina p18 / Melanoma / Proteínas de Neoplasias Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Inibidor de Quinase Dependente de Ciclina p18 / Melanoma / Proteínas de Neoplasias Idioma: En Ano de publicação: 2016 Tipo de documento: Article