Influence of Protonation State on the Excited State Dynamics of a Photobiologically Active Ru(II) Dyad.
J Phys Chem A
; 120(32): 6379-88, 2016 Aug 18.
Article
em En
| MEDLINE
| ID: mdl-27459188
ABSTRACT
The influence of ligand protonation on the photophysics of a ruthenium (Ru) dyad bearing the 2-(1-pyrenyl)-1H-imidazo[4,5-f][1,10]-phenanthroline (ippy) ligand was investigated by time-resolved transient absorption spectroscopy. It was found that changes in the protonation state of the imidazole group led to changes in the electronic configuration of the lowest lying excited state. Formation of the fully deprotonated imidazole anion resulted in excited state signatures that were consistent with a low-lying intraligand (IL) triplet state. This assignment was supported by time-dependent density functional theory (TDDFT) calculations. IL triplet states have been suggested to be potent mediators of photodynamic effects. Thus, these results are of interest in the design of Ru metal complexes as photosensitizers (PSs) for photodynamic therapy (PDT).
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Base de dados:
MEDLINE
Assunto principal:
Compostos Organometálicos
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Fenantrolinas
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Prótons
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Teoria Quântica
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Rutênio
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Fármacos Fotossensibilizantes
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article