Identification and Application of Antitarget Activity Hotspots to Guide Compound Optimization.

Hessler, Gerhard; Matter, Hans; Schmidt, Friedemann; Giegerich, Clemens; Wang, Li-Hsing; Güssregen, Stefan; Baringhaus, Karl-Heinz.

Afiliação

Hessler G; R&D, LGCR, Structure, Design and Informatics, Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Building G838, D-65926 Frankfurt am Main, Germany phone/fax: ++49-69-305-40098. Gerhard.Hessler@sanofi-aventis.com.
Matter H; R&D, LGCR, Structure, Design and Informatics, Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Building G838, D-65926 Frankfurt am Main, Germany phone/fax: ++49-69-305-40098.
Schmidt F; R&D, LGCR, Structure, Design and Informatics, Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Building G838, D-65926 Frankfurt am Main, Germany phone/fax: ++49-69-305-40098.
Giegerich C; R&D, LGCR, Structure, Design and Informatics, Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Building G838, D-65926 Frankfurt am Main, Germany phone/fax: ++49-69-305-40098.
Wang LH; R&D, LGCR, Structure, Design and Informatics, Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Building G838, D-65926 Frankfurt am Main, Germany phone/fax: ++49-69-305-40098.
Güssregen S; R&D, LGCR, Structure, Design and Informatics, Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Building G838, D-65926 Frankfurt am Main, Germany phone/fax: ++49-69-305-40098.
Baringhaus KH; R&D, LGCR, Structure, Design and Informatics, Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Building G838, D-65926 Frankfurt am Main, Germany phone/fax: ++49-69-305-40098.

Mol Inform ; 30(11-12): 996-1008, 2011 Dec.

Article em En | MEDLINE | ID: mdl-27468154