The ability of apolipoprotein E fragments to promote intraneuronal accumulation of amyloid beta peptide 42 is both isoform and size-specific.

Dafnis, Ioannis; Argyri, Letta; Sagnou, Marina; Tzinia, Athina; Tsilibary, Effie C; Stratikos, Efstratios; Chroni, Angeliki

Dafnis, Ioannis; Argyri, Letta; Sagnou, Marina; Tzinia, Athina; Tsilibary, Effie C; Stratikos, Efstratios; Chroni, Angeliki.

Afiliação

Dafnis I; Institute of Biosciences and Applications, National Center for Scientific Research "Demokritos", Agia Paraskevi, Athens 15310, Greece.
Argyri L; Institute of Biosciences and Applications, National Center for Scientific Research "Demokritos", Agia Paraskevi, Athens 15310, Greece.
Sagnou M; Institute of Biosciences and Applications, National Center for Scientific Research "Demokritos", Agia Paraskevi, Athens 15310, Greece.
Tzinia A; Institute of Biosciences and Applications, National Center for Scientific Research "Demokritos", Agia Paraskevi, Athens 15310, Greece.
Tsilibary EC; Institute of Biosciences and Applications, National Center for Scientific Research "Demokritos", Agia Paraskevi, Athens 15310, Greece.
Stratikos E; Protein Chemistry Laboratory, Institute of Nuclear and Radiological Sciences and Technology, Energy and Safety, National Center for Scientific Research "Demokritos", Agia Paraskevi, Athens 15310, Greece.
Chroni A; Institute of Biosciences and Applications, National Center for Scientific Research "Demokritos", Agia Paraskevi, Athens 15310, Greece.

Sci Rep ; 6: 30654, 2016 08 01.

Article em En | MEDLINE | ID: mdl-27476701

Assuntos

Peptídeos beta-Amiloides/metabolismo; Apolipoproteína E4/metabolismo; Apolipoproteínas E/metabolismo; Neurônios/metabolismo; Fragmentos de Peptídeos/metabolismo; Apolipoproteína E4/química; Apolipoproteínas E/química; Humanos; Conformação Proteica; Dobramento de Proteína; Isoformas de Proteínas/química; Isoformas de Proteínas/metabolismo; Estabilidade Proteica; Células Tumorais Cultivadas

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Apolipoproteínas E / Fragmentos de Peptídeos / Peptídeos beta-Amiloides / Apolipoproteína E4 / Neurônios Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google