Direct Catalytic Asymmetric Mannich Reaction with Dithiomalonates as Excellent Mannich Donors: Organocatalytic Synthesis of (R)-Sitagliptin.

Bae, Han Yong; Kim, Mun Jong; Sim, Jae Hun; Song, Choong Eui.

Afiliação

Bae HY; Department of Chemistry, Sungkyunkwan University, Jangan, Suwon, 440-746, Korea.
Kim MJ; Max-Planck-Institut für Kohlenforschung, Kaiser-Wilhelm-Platz 1, 45470, Mülheim an der Ruhr, Germany.
Sim JH; Department of Chemistry, Sungkyunkwan University, Jangan, Suwon, 440-746, Korea.
Song CE; Department of Chemistry, Sungkyunkwan University, Jangan, Suwon, 440-746, Korea.

Angew Chem Int Ed Engl ; 55(36): 10825-9, 2016 08 26.

Article em En | MEDLINE | ID: mdl-27486059