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No Evidence of Reactivation of Hepatitis B Virus Among Patients Treated With Ledipasvir-Sofosbuvir for Hepatitis C Virus Infection.
Sulkowski, Mark S; Chuang, Wan-Long; Kao, Jia-Horng; Yang, Jenny C; Gao, Bing; Brainard, Diana M; Han, Kwang-Hyub; Gane, Edward.
Afiliação
  • Sulkowski MS; Johns Hopkins University School of Medicine, Baltimore, Maryland.
  • Chuang WL; Kaohsiung Medical University Hospital.
  • Kao JH; National Taiwan University College of Medicine and Hospital, Taipei, Taiwan.
  • Yang JC; Gilead Sciences, Foster City, California.
  • Gao B; Gilead Sciences, Foster City, California.
  • Brainard DM; Gilead Sciences, Foster City, California.
  • Han KH; Yonsei University College of Medicine, Seoul, South Korea.
  • Gane E; New Zealand Liver Transplant Unit, Auckland City Hospital.
Clin Infect Dis ; 63(9): 1202-1204, 2016 11 01.
Article em En | MEDLINE | ID: mdl-27486112
Postmarketing cases of hepatitis B virus (HBV) reactivation during hepatitis C treatment have been reported. We analyzed serum samples from patients in a clinical trial of ledipasvir-sofosbuvir in Taiwan and Korea. Of the 173 patients enrolled, 103 (60%) had been previously infected with HBV. None showed evidence of HBV reactivation.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / Ativação Viral / Benzimidazóis / Vírus da Hepatite B / Hepatite C / Fluorenos / Sofosbuvir / Hepatite B Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / Ativação Viral / Benzimidazóis / Vírus da Hepatite B / Hepatite C / Fluorenos / Sofosbuvir / Hepatite B Idioma: En Ano de publicação: 2016 Tipo de documento: Article