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Erasure of DNA methylation, genomic imprints, and epimutations in a primordial germ-cell model derived from mouse pluripotent stem cells.
Miyoshi, Norikatsu; Stel, Jente M; Shioda, Keiko; Qu, Na; Odajima, Junko; Mitsunaga, Shino; Zhang, Xiangfan; Nagano, Makoto; Hochedlinger, Konrad; Isselbacher, Kurt J; Shioda, Toshi.
Afiliação
  • Miyoshi N; Massachusetts General Hospital Center for Cancer Research, Charlestown, MA 02129;
  • Stel JM; Massachusetts General Hospital Center for Cancer Research, Charlestown, MA 02129; Institute for Environmental Studies Vrije Universiteit, Amsterdam 1081 HV, The Netherlands;
  • Shioda K; Massachusetts General Hospital Center for Cancer Research, Charlestown, MA 02129;
  • Qu N; Massachusetts General Hospital Center for Cancer Research, Charlestown, MA 02129;
  • Odajima J; Massachusetts General Hospital Center for Cancer Research, Charlestown, MA 02129;
  • Mitsunaga S; Massachusetts General Hospital Center for Cancer Research, Charlestown, MA 02129;
  • Zhang X; Department of Obstetrics and Gynecology, McGill University and Research Institute of McGill University Health Centre, Montreal, QC, Canada H4A 3J1;
  • Nagano M; Department of Obstetrics and Gynecology, McGill University and Research Institute of McGill University Health Centre, Montreal, QC, Canada H4A 3J1;
  • Hochedlinger K; Massachusetts General Hospital Center for Cancer Research, Charlestown, MA 02129; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Cambridge, MA 02138.
  • Isselbacher KJ; Massachusetts General Hospital Center for Cancer Research, Charlestown, MA 02129; kisselbacher@mgh.harvard.edu tshioda@mgh.harvard.edu.
  • Shioda T; Massachusetts General Hospital Center for Cancer Research, Charlestown, MA 02129; kisselbacher@mgh.harvard.edu tshioda@mgh.harvard.edu.
Proc Natl Acad Sci U S A ; 113(34): 9545-50, 2016 08 23.
Article em En | MEDLINE | ID: mdl-27486249
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Genoma / Impressão Genômica / Células-Tronco Pluripotentes / Epigênese Genética / Desmetilação do DNA / Células Germinativas Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Genoma / Impressão Genômica / Células-Tronco Pluripotentes / Epigênese Genética / Desmetilação do DNA / Células Germinativas Idioma: En Ano de publicação: 2016 Tipo de documento: Article