Fulminant Epstein-Barr virus-associated hemophagocytic syndrome in a renal transplant patient and review of the literature.
Transpl Infect Dis
; 18(5): 795-800, 2016 Oct.
Article
em En
| MEDLINE
| ID: mdl-27496079
ABSTRACT
We describe a rare fulminant case of Epstein-Barr virus-associated hemophagocytic syndrome (HPS) in a 37-year-old female renal transplant patient, indistinguishable from severe sepsis clinically and in the laboratory. HPS involves rapidly escalating immune system activation, resulting in a cytokine cascade, which can, especially in immunocompromised patients, lead to multi-organ failure, and even death. Thirty-two Herpesviridae-associated HPS cases in renal transplant patients have been reported and are reviewed. Overall mortality is 47% (15/32 cases).
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Base de dados:
MEDLINE
Assunto principal:
Antivirais
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Transplante de Rim
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Herpesvirus Humano 4
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Infecções por Vírus Epstein-Barr
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Linfo-Histiocitose Hemofagocítica
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Glomerulonefrite por IGA
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Insuficiência de Múltiplos Órgãos
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article