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Quercetin ameliorates paclitaxel-induced neuropathic pain by stabilizing mast cells, and subsequently blocking PKCε-dependent activation of TRPV1.
Gao, Wei; Zan, Yan; Wang, Zai-Jie Jim; Hu, Xiao-Yu; Huang, Fang.
Afiliação
  • Gao W; Jiangsu Key Laboratory of TCM Evaluation and Translational Research, Department of Pharmacology of Chinese Materia Medica, China Pharmaceutical University, Nanjing, China.
  • Zan Y; Jiangsu Key Laboratory of TCM Evaluation and Translational Research, Department of Pharmacology of Chinese Materia Medica, China Pharmaceutical University, Nanjing, China.
  • Wang ZJ; Department of Biopharmaceutical Sciences and Cancer Center, University of Illinois, Chicago, IL, USA.
  • Hu XY; Department of Biopharmaceutical Sciences and Cancer Center, University of Illinois, Chicago, IL, USA.
  • Huang F; Jiangsu Key Laboratory of TCM Evaluation and Translational Research, Department of Pharmacology of Chinese Materia Medica, China Pharmaceutical University, Nanjing, China.
Acta Pharmacol Sin ; 37(9): 1166-77, 2016 Sep.
Article em En | MEDLINE | ID: mdl-27498772
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quercetina / Paclitaxel / Proteína Quinase C-épsilon / Canais de Cátion TRPV / Mastócitos / Neuralgia / Antineoplásicos Fitogênicos Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quercetina / Paclitaxel / Proteína Quinase C-épsilon / Canais de Cátion TRPV / Mastócitos / Neuralgia / Antineoplásicos Fitogênicos Idioma: En Ano de publicação: 2016 Tipo de documento: Article